CAJ | 학술논문

目的探讨睡眠期间发生缓慢性心律失常的阻塞性睡眠呼吸暂停(OSA)患者的临床特点,并分析缓慢性心律失常的发生与血氧饱和度下降的关系.方法 1999年9月至2005年4月对北京阜外心血管病医院和北京同仁医院确诊的203例OSA的患者,在接受多导睡眠仪睡眠检查后2周内进行24 h动态心电图检查,分析其发生缓慢性心律失常患者的临床特点.结果与未合并缓慢性心律失常者相比,夜间发生缓慢性心律失常的OSA患者体重指数增高(24±6比34±5,P<0.05);呼吸紊乱指数增高[(25±5)次/h比(63±15)次/h,P<0.01];最低血氧饱和度下降[(75 ±11)%比(63±15)%,P<0.05],但缓慢性心律失常的发生与最低血氧饱和度间没有明确的线性关系.结论肥胖而严重的OSA患者睡眠期间缓慢性心律失常的发生率增高.在心律失常诊治过程中,尤其是对夜间发生缓慢性心律失常的患者,应该考虑到OSA的存在.
목적 탐토수면기간발생완만성심률실상적조새성수면호흡잠정(OSA)환자적림상특점,병분석완만성심률실상적발생여혈양포화도하강적관계.방법 1999년9월지2005년4월대북경부외심혈관병의원화북경동인의원학진적203례OSA적환자,재접수다도수면의수면검사후2주내진행24 h동태심전도검사,분석기발생완만성심률실상환자적림상특점.결과 여미합병완만성심률실상자상비,야간발생완만성심률실상적OSA환자체중지수증고(24±6비34±5,P<0.05);호흡문란지수증고[(25±5)차/h비(63±15)차/h,P<0.01];최저혈양포화도하강[(75 ±11)%비(63±15)%,P<0.05],단완만성심률실상적발생여최저혈양포화도간몰유명학적선성관계.결론 비반이엄중적OSA환자수면기간완만성심률실상적발생솔증고.재심률실상진치과정중,우기시대야간발생완만성심률실상적환자,응해고필도OSA적존재.
Objective To analyze the relations between obstructive sleep apnea and bradyarrhythmia.Methods From 1999 to 2005,203 patients who came from Bering Tongren Hospital and Fuwai Hospital were found to have sleep apnea in an ambulatory study. A Hoher electrecardiogram was recorded for 24 hours within 2 weeks after patients were diagnosed as obstructive sleep apnem Results Nocturnal episodes of bradyarrhythmia were identified in 12(5.9%)of 203 patients.Body mass index and respiratory disturbance index in patients with bradyarrhythmia(n=12)were higher than those in patientswithour bradyarrhymia(n=191)(34±5 735.24±6 and 63±15 vs.25±5,respectively,both P<0.01).There was a significant difference in end-apneic oxygen saturation in apnea/hypopnea episodes with and without bradyarrhythmia(63%±15% vs.75%±11%,P<0.05).A linear relation between end-apneic oxygen saturation and number of sinus arrests and heart blocks was not found.Conclusions Patients with apnea-associated bradyarrhythmia have higher body mflgB index and higher respiratory disturbance index than patients without bradyarrhythmi&Bradyarrhythmia occurres independently from decrease in oxygen saturation.