CAJ | 학술논문

瘢痕疙瘩是一种难治性的异常瘢痕,目前药物治疗是一种比较常规的方法.作者查阅了国内外近年的相关文献资料进行分析与综述,阐述各类药物治疗瘢痕疙瘩的机制和临床应用情况.临床使用最广泛的药物包括皮质类固醇激素、抗代谢药、免疫调节剂、类维生素A.另外钙通道阻滞剂、抗组胺药等对治疗瘢痕疙瘩也有一定的疗效.药物在治疗和预防瘢痕疙瘩复发方面有重要的用途和意义.
반흔흘탑시일충난치성적이상반흔,목전약물치료시일충비교상규적방법.작자사열료국내외근년적상관문헌자료진행분석여종술,천술각류약물치료반흔흘탑적궤제화림상응용정황.림상사용최엄범적약물포괄피질류고순격소、항대사약、면역조절제、류유생소A.령외개통도조체제、항조알약등대치료반흔흘탑야유일정적료효.약물재치료화예방반흔흘탑복발방면유중요적용도화의의.
Keloid represents a form of pathologic wound healing, drug treatment is a conventional approach for keloid. Domestic and foreign literature about this field is reviewed to state the mechanism of various types of drug treatment and clinical application. The drugs most extensivly used clinically are corticosteroids, anti-metabolism drugs, immunomodulatory agents, retinoids, while calcium channel blockers, antihistamine drugs and some others also have certain efficacy. Drugs have important significance in keloid treatment and prevention of recurrence.