中华妇幼临床医学杂志（电子版）
中華婦幼臨床醫學雜誌（電子版）
중화부유림상의학잡지（전자판）
CHINESE JOURNAL OF OBSTETRICS & GYNECOLOGY AND PEDIATRICS(ELECTRONIC VERSION)
2012年
4期
437-440
,共4页
孙德宏%于永锋%赵桂娟%张定荣%徐书珍
孫德宏%于永鋒%趙桂娟%張定榮%徐書珍
손덕굉%우영봉%조계연%장정영%서서진
肠道病毒71型%手足口病%免疫功能%全身炎症反应综合征%儿童
腸道病毒71型%手足口病%免疫功能%全身炎癥反應綜閤徵%兒童
장도병독71형%수족구병%면역공능%전신염증반응종합정%인동
enterovirus 71 (EV71)%hand-foot-mouth disease%immune function%systemic inflammatory response syndrome%child
手足口病(HFMD)患儿肠道病毒71 (EV71)感染可导致中枢神经、呼吸系统损害,引发脑炎、急性弛缓性麻痹、脑水肿和心肌炎等,个别重型HFMD患儿病情进展快,易致死亡.HFMD发病机制可能与病毒感染所致免疫功能异常有关,尤其是细胞免疫功能低下.此外,EV71病毒感染导致的全身炎症反应综合征(SIRS)也可能参与HFMD的发病.因此早期对HFMD患儿进行细胞免疫支持治疗,并阻断SIRS发展,对改善预后意义重大.
手足口病(HFMD)患兒腸道病毒71 (EV71)感染可導緻中樞神經、呼吸繫統損害,引髮腦炎、急性弛緩性痳痺、腦水腫和心肌炎等,箇彆重型HFMD患兒病情進展快,易緻死亡.HFMD髮病機製可能與病毒感染所緻免疫功能異常有關,尤其是細胞免疫功能低下.此外,EV71病毒感染導緻的全身炎癥反應綜閤徵(SIRS)也可能參與HFMD的髮病.因此早期對HFMD患兒進行細胞免疫支持治療,併阻斷SIRS髮展,對改善預後意義重大.
수족구병(HFMD)환인장도병독71 (EV71)감염가도치중추신경、호흡계통손해,인발뇌염、급성이완성마비、뇌수종화심기염등,개별중형HFMD환인병정진전쾌,역치사망.HFMD발병궤제가능여병독감염소치면역공능이상유관,우기시세포면역공능저하.차외,EV71병독감염도치적전신염증반응종합정(SIRS)야가능삼여HFMD적발병.인차조기대HFMD환인진행세포면역지지치료,병조단SIRS발전,대개선예후의의중대.
Children with hand-foot-mouth disease (HFMD) which caused by enterovirus 71 (EV71) can appear central nervous and respiratory system damage.Meanwhile,EV71 can cause encephalitis,brain edema and myocarditis.Some severe cases are prone to death.The pathogenesis of HFMD is likely related to immune disorders caused by EV71 infection. Additional, systemic inflammatory response syndrome (SIRS) may play an important role in attack.As a result,it is necessary for us to take cellular immune support treatment in time and block SIRS development.It is also significant for children with HFMD to improve the prognosis.
