中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2012年
2期
182-184
,共3页
蔡国华%孙振东%亓峰%雷加吉%刁力为%张庆华%吴乃石
蔡國華%孫振東%亓峰%雷加吉%刁力為%張慶華%吳迺石
채국화%손진동%기봉%뢰가길%조력위%장경화%오내석
心脏移植/方法%移植,同种%移植,异位
心髒移植/方法%移植,同種%移植,異位
심장이식/방법%이식,동충%이식,이위
Heart transplantation/MT%Transplantation,homologous%Transplantation,heterotopic
目的 总结建立大鼠同种异位心脏移植模型的经验、方法及体会.方法 行大鼠同种异位心脏移植(Ono术式)120例.其中预备实验60例,正式实验60例.结果 预备实验手术成功率为45％,正式实验手术成功率为85％.正式实验整个手术时间为(74.3±17.1)min,供心缺血时间(29.6±10.3)min,供心摘取时间约(7.9±4.2)min.移植心存活时间为(11.1±5.7)d；5例心脏移植后大鼠长期存活,最大体重达740 g.结论 成功制备大鼠心脏移植模型,良好手术技术和严格的围手术期处理同等重要.
目的 總結建立大鼠同種異位心髒移植模型的經驗、方法及體會.方法 行大鼠同種異位心髒移植(Ono術式)120例.其中預備實驗60例,正式實驗60例.結果 預備實驗手術成功率為45％,正式實驗手術成功率為85％.正式實驗整箇手術時間為(74.3±17.1)min,供心缺血時間(29.6±10.3)min,供心摘取時間約(7.9±4.2)min.移植心存活時間為(11.1±5.7)d；5例心髒移植後大鼠長期存活,最大體重達740 g.結論 成功製備大鼠心髒移植模型,良好手術技術和嚴格的圍手術期處理同等重要.
목적 총결건립대서동충이위심장이식모형적경험、방법급체회.방법 행대서동충이위심장이식(Ono술식)120례.기중예비실험60례,정식실험60례.결과 예비실험수술성공솔위45％,정식실험수술성공솔위85％.정식실험정개수술시간위(74.3±17.1)min,공심결혈시간(29.6±10.3)min,공심적취시간약(7.9±4.2)min.이식심존활시간위(11.1±5.7)d；5례심장이식후대서장기존활,최대체중체740 g.결론 성공제비대서심장이식모형,량호수술기술화엄격적위수술기처리동등중요.
Objective To summarize the method and experience of the model of rat heterotopic heart transplantation and to improve the rate of success of the experiment.Methods 120 heterotopic heart transplantations were performed by Ono's way,including 60 prepared transplantations and 60 formal transplantations.Results Rate of success of prepared transplantations was 45％,and formal transplantation was 85％.Mean time of formal operation was (74.3±17.1)min,removal time of the donor heart was (7.9±4.2)min,ischemia time was (29.6±10.3) min and the survival time of allograft was (11.1±5.7)days.5 of the recipients had a long-term survival,and the maximum weight was 740 g.Conclusions Good surgical technique and rigorous perioperative management is very important in setting up the rat model of heterotopic heart transplantation.
