生命科学仪器
生命科學儀器
생명과학의기
LIFE SCIENCES INSTRUMENT
2011年
5期
39-42
,共4页
气相色谱%不确定度%α-硫辛酸%残留量%外标工作曲线
氣相色譜%不確定度%α-硫辛痠%殘留量%外標工作麯線
기상색보%불학정도%α-류신산%잔류량%외표공작곡선
Gas chromatography%Uncertainty%α-lipoic acid%Residual organic solvents%External standard working curve method
研究了α-硫辛酸中有机溶剂残留量气相色谱定量方法的测量不确定度的评定方法。通过建立数学模型,对测量过程的不确定度来源如：样品称样量、定容体积、工作曲线、测试方法的回收率和重复性的各不确定度分量进行分析评定和量化,计算了合成不确定度和扩展不确定度,α-硫辛酸中有机溶剂残留量的GC定量结果表示为乙醚（0.252±0.006）%;k=2;异丙醚（0.092±0.002）%;k=2。本试验的不确定度主要由外标工作曲线所引起。
研究瞭α-硫辛痠中有機溶劑殘留量氣相色譜定量方法的測量不確定度的評定方法。通過建立數學模型,對測量過程的不確定度來源如：樣品稱樣量、定容體積、工作麯線、測試方法的迴收率和重複性的各不確定度分量進行分析評定和量化,計算瞭閤成不確定度和擴展不確定度,α-硫辛痠中有機溶劑殘留量的GC定量結果錶示為乙醚（0.252±0.006）%;k=2;異丙醚（0.092±0.002）%;k=2。本試驗的不確定度主要由外標工作麯線所引起。
연구료α-류신산중유궤용제잔류량기상색보정량방법적측량불학정도적평정방법。통과건립수학모형,대측량과정적불학정도래원여：양품칭양량、정용체적、공작곡선、측시방법적회수솔화중복성적각불학정도분량진행분석평정화양화,계산료합성불학정도화확전불학정도,α-류신산중유궤용제잔류량적GC정량결과표시위을미（0.252±0.006）%;k=2;이병미（0.092±0.002）%;k=2。본시험적불학정도주요유외표공작곡선소인기。
The evaluation method of measurement uncertainty for the determination of residual solvents in α-lipoic acid by GC was studied.Through establishing the mathematical model,the uncertainty sources arising from the determining procedures such as the volume of sample,the weight of sample,standard working curve,recovery and repeatability of measurement method were analyzed.Each component of uncertainty was evaluated and quantified.The combined standard uncertainty and the expanded uncertainty were calculated.The quantitative results including the expanded uncertainty of residual solvents in α-lipoic acid were expressed as（0.252±0.006）%;k=2 for diethyl ether and（0.092±0.002）%;k=2 for di-iso-propyl ether.The uncertainty of this experiment is mainly caused by external standard working curve.
