中国医药
中國醫藥
중국의약
CHINA MEDICINE
2009年
9期
683-684
,共2页
急性脑梗死%S 100 β蛋白%尿酸
急性腦梗死%S 100 β蛋白%尿痠
급성뇌경사%S 100 β단백%뇨산
Acute cerebral infarction%S 100 β protein%Uric acid
目的 探讨急性脑梗死患者血清S 100 β蛋白和尿酸含量变化的意义及其机制.方法 测定54例急性脑梗死患者及21例正常人血清S 100 β蛋白和尿酸的含量,观察比较急性脑梗死患者在不同病情、不同梗死面积时的血清S 100 β蛋白和尿酸含量变化.结果 急性脑梗死患者血清S 100 β蛋白浓度[(0.458±0.109)μg/L]和尿酸浓度[(415.3±41.5)μmol/L]浓度明显高于对照组[分别为(0.057±0.024)μg/L和(261.5±30.1) μmol/L],差异有统计学意义(P<0.01).随着神经功能缺损程度的加重和梗死面积的增大,血清S 100 β和尿酸含量亦明显升高.结论 S 100 β蛋白与尿酸一样可作为预测急性脑梗死患者病情严重程度及预后的生化指标,二者相结合进行评价意义更大.
目的 探討急性腦梗死患者血清S 100 β蛋白和尿痠含量變化的意義及其機製.方法 測定54例急性腦梗死患者及21例正常人血清S 100 β蛋白和尿痠的含量,觀察比較急性腦梗死患者在不同病情、不同梗死麵積時的血清S 100 β蛋白和尿痠含量變化.結果 急性腦梗死患者血清S 100 β蛋白濃度[(0.458±0.109)μg/L]和尿痠濃度[(415.3±41.5)μmol/L]濃度明顯高于對照組[分彆為(0.057±0.024)μg/L和(261.5±30.1) μmol/L],差異有統計學意義(P<0.01).隨著神經功能缺損程度的加重和梗死麵積的增大,血清S 100 β和尿痠含量亦明顯升高.結論 S 100 β蛋白與尿痠一樣可作為預測急性腦梗死患者病情嚴重程度及預後的生化指標,二者相結閤進行評價意義更大.
목적 탐토급성뇌경사환자혈청S 100 β단백화뇨산함량변화적의의급기궤제.방법 측정54례급성뇌경사환자급21례정상인혈청S 100 β단백화뇨산적함량,관찰비교급성뇌경사환자재불동병정、불동경사면적시적혈청S 100 β단백화뇨산함량변화.결과 급성뇌경사환자혈청S 100 β단백농도[(0.458±0.109)μg/L]화뇨산농도[(415.3±41.5)μmol/L]농도명현고우대조조[분별위(0.057±0.024)μg/L화(261.5±30.1) μmol/L],차이유통계학의의(P<0.01).수착신경공능결손정도적가중화경사면적적증대,혈청S 100 β화뇨산함량역명현승고.결론 S 100 β단백여뇨산일양가작위예측급성뇌경사환자병정엄중정도급예후적생화지표,이자상결합진행평개의의경대.
Objective To investigate the changes of serum S 100 β protein and uric acid(UA) content in patients with acute cerebral infarction(ACI). Methods The level of serum S 100 βand UA in 54 patients with ACI and 21 normal controls were measured, The changes of S 100 β and UA were compared among patients of different pathogenetic condition and infarction area. The correlation analysis between S 100 β and UA was also made. ResultsCompared with control group,the levels of serum S 100 β and UA in patients with ACI increased significantly (all P <0.01 ). The level of serum S 100 β and UA increased with the score of neurofunction detection and infarction area. Conclusions The S 100 β protein and UA protein can be indexes of predicting the neurofunction of ACT and a combination with each other provides a higher clinical significance.
