CAJ | 학술논문

目的探讨益气活血通络法对特发性肺间质纤维化(IPF)气虚血瘀证患者生存质量的改善作用.方法符合中西医诊断标准的IPF患者30例,采用自身前后对照的方法,给予益气活血通络汤口服,每日1剂,每服200 mL,每日服2次.3个月为1疗程,观察2个疗程.以呼吸疾病问卷(SGRQ)作为测评工具,观察患者生存质量的改善情况.结果治疗6个月时SGRQ中呼吸症状评分、活动受限评分、总分积分均有所降低,与治疗前相比有显著性差异(P＜0.05);疾病影响评分也有所降低,但与治疗前相比未见显著性差异(P＞0.05).结论益气活血通络法对改善IPF气虚血瘀证患者生存质量具有显著意义.
목적 탐토익기활혈통락법대특발성폐간질섬유화(IPF)기허혈어증환자생존질량적개선작용.방법 부합중서의진단표준적IPF환자30례,채용자신전후대조적방법,급여익기활혈통락탕구복,매일1제,매복200 mL,매일복2차.3개월위1료정,관찰2개료정.이호흡질병문권(SGRQ)작위측평공구,관찰환자생존질량적개선정황.결과 치료6개월시SGRQ중호흡증상평분、활동수한평분、총분적분균유소강저,여치료전상비유현저성차이(P＜0.05);질병영향평분야유소강저,단여치료전상비미견현저성차이(P＞0.05).결론 익기활혈통락법대개선IPF기허혈어증환자생존질량구유현저의의.
Objective To discuss the effect of the therapy of supplementing qi,activating blood circulation and free the collateral vessels on life quality in patients with the syndrome of qi deficiency and blood stasis of idiopathic pulmonary fibrosis(IPF).Method The patients(n=30)accorded with the diagnostic standard of Chinese and Western medicine were chosen and given Yiqihuoxuetongluo Decoction orally,one decoction and twice a day(200 mL once).One therapeutic course was 3 months and the patients were observed for 2 courses.St.George's respiratory-disease questionnaire(SGRQ)was taken as an examination tool to observe the improvement of life quality in the patients.Result After th treatment for 6 months the scores of respiratory symptoms and activity limitation,and the total integral decreased in SGRQ,and there was a difference before and after the treatment(P＜0.05).The score of disease impact decreased a little and there was a difference before and after the treatment(P＞0.05).Conclusion The therapy of supplementing qi,activating blood circulation and free the collateral vessels is significant to the life quality of the patients with the syndrome of qi deficiency and blood stasis of IPF.