CAJ | 학술논문

目的探讨失血性休克对重度颅脑损伤并发应激性溃疡的影响.方法 428例重度颅脑损伤患者根据有无合并失血性休克分为两组(休克组133例、无休克组295例),观察两组发生应激性溃疡、胃液和血液的pH值等情况.结果 428例重度颅脑损伤患者并发应激性溃疡112例(26.2%),其中休克组75例,占失血性休克的56.4%(75/133),无休克组37例,占无失血性休克的12.5%(37/295),两组比较差异有统计学意义(X2=91.23,P＜0.01);伤后第2天两组患者血液中的pH值分别为:7.24±0.11和7.32±0.17,两组比较差异有统计学意义(t=5.797,P＜0.01),第7天两组血液中的pH值分别为:(7.34±0.11)和(7.33±0.15),两组比较差异无统计学意义(t=0.769,P＞0.05);伤后第2天两组患者胃液中的pH值分别为:(2.88±0.29)和(2.84±0.35),第7天胃液中的pH值分别为:(3.21±1.44)和(3.45±1.05),两组比较均无统计学意义(t=1.231、1.714,P＞0.05).结论失血性休克在重型颅脑损伤并发应激性溃疡中起重要作用.
목적 탐토실혈성휴극대중도로뇌손상병발응격성궤양적영향.방법 428례중도로뇌손상환자근거유무합병실혈성휴극분위량조(휴극조133례、무휴극조295례),관찰량조발생응격성궤양、위액화혈액적pH치등정황.결과 428례중도로뇌손상환자병발응격성궤양112례(26.2%),기중휴극조75례,점실혈성휴극적56.4%(75/133),무휴극조37례,점무실혈성휴극적12.5%(37/295),량조비교차이유통계학의의(X2=91.23,P＜0.01);상후제2천량조환자혈액중적pH치분별위:7.24±0.11화7.32±0.17,량조비교차이유통계학의의(t=5.797,P＜0.01),제7천량조혈액중적pH치분별위:(7.34±0.11)화(7.33±0.15),량조비교차이무통계학의의(t=0.769,P＞0.05);상후제2천량조환자위액중적pH치분별위:(2.88±0.29)화(2.84±0.35),제7천위액중적pH치분별위:(3.21±1.44)화(3.45±1.05),량조비교균무통계학의의(t=1.231、1.714,P＞0.05).결론 실혈성휴극재중형로뇌손상병발응격성궤양중기중요작용.
Objective To study the role of hemorrhagic shock in severe eraniocerebral trauma with stress ulcer.Methods The clinical data of 428 patients of sevcere craniocerebral tramna in 0111"hospital from January 2001 to January 2009 were divided into two groups according to whether or not merging with hemorrhagic shock.The incidence of stress ulcer in two groups was calculated and the PH ofgastric juice and blood in different periods were measured.Results Stress ulcerdevelopedin 56.4%(75/133)ofpatientswith hemorrhagic shockand 12.5%(37/295)of patients with hemorrhagic shock-free,with significant difference between the two groups(P＜0.01).Blood pH differed significantly(P＜0.01)on 2d,but not on 7d(P＞0.05)after injury between the two groups.There wag no significant difference in gastric juice pH on 2d and 7d after injury between the two groups(P＞0.05).Condusion Hemorrhagie shock phys an important role in severe craniocerebral trauma with stress deer.