CAJ | 학술논문

肿瘤微环境对于肿瘤发生、发展的作用以及对辅助化疗、新辅助化疗疗效的影响越来越受到重视.研究表明乳腺癌微环境尤其是肿瘤间质纤维母细胞(CAF)及其合成的基质细胞衍生因子-1( SDF-1)和胶原,可对新辅助化疗产生重要的影响.
종류미배경대우종류발생、발전적작용이급대보조화료、신보조화료료효적영향월래월수도중시.연구표명유선암미배경우기시종류간질섬유모세포(CAF)급기합성적기질세포연생인자-1( SDF-1)화효원,가대신보조화료산생중요적영향.
Recently many studies have focused on the roles that tumor microenvironment plays in the occurrence and development of tumors,and the therapeutic effects of adjuvant chemotherapy and neoadjuvant chemotherapy.Recent researches show that tumor microenvironment has an obvious impact on the therapeutic effects of neoadjuvant chemotherapy,which mainly includes cancer-associated fibroblasts (CAF),stromal cell derived factor-1 (SDF-1) and collagens.