CAJ | 학술논문

目的观察附子理中汤治疗化疗消化道反应的临床疗效.方法对160例接受化疗的肿瘤患者进行临床研究.将160例患者随机分为观察组和对照组各80例,两组选用相同的化疗方案,化疗前均用盐酸格拉司琼静脉点滴止吐,化疗期间观察组每日服用附子理中汤,对照组每日以甲氧氯普胺10mg、苯海拉明20 mg肌内注射.结果观察组恶心呕吐、食欲下降、进食差、腹胀、便秘症状发生率低,明显优于对照组,经统计学分析,P<0.05差异有统计学意义.结论附子理中汤能显著减轻化疗消化道反应,值得临床推广应用.
목적관찰부자리중탕치료화료소화도반응적림상료효.방법대160례접수화료적종류환자진행림상연구.장160례환자수궤분위관찰조화대조조각80례,량조선용상동적화료방안,화료전균용염산격랍사경정맥점적지토,화료기간관찰조매일복용부자리중탕,대조조매일이갑양록보알10mg、분해랍명20 mg기내주사.결과관찰조악심구토、식욕하강、진식차、복창、편비증상발생솔저,명현우우대조조,경통계학분석,P<0.05차이유통계학의의.결론부자리중탕능현저감경화료소화도반응,치득림상추엄응용.
Objective To observe the clinical effect of fuzilizhongtang in Treating gastrointestinal reac-tion due to chemotherapy for malignant tumor. Methods 160 post-chemotherapy tumor patients treated with the same chemotherapy were randomly divided into two equal groups. The control and the fuzilizhongtang group re-ceived the same chemotherapeutic treatments with intravenous Granisetron Hydrochloride before the chemothera-py for preventing vomiting. During the chemotherapy period, the control group were intramuscularly injected with 10 mg metoclopramide and 20 mg Diphenhydramine while the fuzilizhongtang group were given fuzilizhongtang per day orally. Results The incidence of nausea and vomiting, loss of appetite, abdominal distention, constipa-tion was significantly lower in fuzilizhongtang group than in control group (P<0.05 or P<0.01). ConclusionFuzilizhongtang can significantly alleviate the gastrointestinal reaction due to chemotherapy for malignant tumor,deserve the clinical expansion.