CAJ | 학술논문

目的探讨经胃镜放置空肠营养管行肠内营养支持(ENFTP)对重症急性胰腺炎患者的临床价值.方法回顾性分析经ENFTP及同期行完全胃肠外营养(TPN)支持的重症急性胰腺炎患者47例及50例,比较两组患者营养支持前及支持后1、2、4周血常规、血糖、肝肾功能、血脂、血钙水平变化、各种并发症发生率、死亡率、营养支持时间、营养支持平均每日费用、机械通气时间、重症监护病房(ICU)监护时间及平均住院时间.结果营养支持4周后,ENFTP组血红蛋白、白蛋白及空腹高血糖较TPN组恢复显著(P值均<0.05);ENFTP组胰周、胆道感染率、导管感染败血症、营养支持时间、营养支持平均每日费用及住院时间均显著低于TPN组(P值均<0.05),此外ENFTP组能更有效改善APACHEⅡ评分(P<0.05).结论 ENFTP在重症急性胰腺炎患者中应用安全经济.
목적 탐토경위경방치공장영양관행장내영양지지(ENFTP)대중증급성이선염환자적림상개치.방법 회고성분석경ENFTP급동기행완전위장외영양(TPN)지지적중증급성이선염환자47례급50례,비교량조환자영양지지전급지지후1、2、4주혈상규、혈당、간신공능、혈지、혈개수평변화、각충병발증발생솔、사망솔、영양지지시간、영양지지평균매일비용、궤계통기시간、중증감호병방(ICU)감호시간급평균주원시간.결과 영양지지4주후,ENFTP조혈홍단백、백단백급공복고혈당교TPN조회복현저(P치균<0.05);ENFTP조이주、담도감염솔、도관감염패혈증、영양지지시간、영양지지평균매일비용급주원시간균현저저우TPN조(P치균<0.05),차외ENFTP조능경유효개선APACHEⅡ평분(P<0.05).결론 ENFTP재중증급성이선염환자중응용안전경제.
Objective To evaluate the clinical value of endoscopically nasojejunal feeding tube placement (ENFTP) for nutritional support in patients with severe acute pancreatitis (SAP). Methods Those SAP patients who treated with ENFTP (n= 47) or with total parenteral nutrition (TPN) (n=50) were retrospectively analyzed for laboratory parameters before and 1,2 and 4 weeks after nutrition support. Outcomes in the two groups were compared with respect to complications,mortality, duration of feeding, feeding costs,mechanical ventilation time and length of ICU or hospital stay. Results Four weeks after nutrition sypport, the hemoglobin and albumin were increased in ENFTP group as compared to TPN groups (P < 0. 05), while the blood sugar was decreased significant in ENFTP group than in TPN group (P<0.05). The incidence of peripancreatic or biliary infection and catheter-related infection were lower in ENFTP group than in TPN group. Duration of feeding and hospital stay were shorter, and nutrition cost was lower in ENFTP group (P<0.05). In addition, the APACHE Ⅱ score was significantly improved in ENFTP group(P<0.05). Conclusion ENFTP seems to be safe and less expensive in treatment of patients with acute pancreatitis.