CAJ | 학술논문

目的研究大叶橐吾的化学成分.方法应用多种色谱方法和色谱材料进行提取、分离和纯化,用各种现代光谱方法解析结构.结果从大叶橐吾根茎的乙醇提取物中分离纯化到四个黄酮醇苷和两个单萜苷,分别为甲基鼠李素-3-O-β-D-芸香糖苷(1),鼠李素-3-O-β-D-芸香糖苷(2),芦丁(3),阿福豆苷(4),桦木苷(5)和3,7-dimethyloct-1-en-3,8-diol-8-O-β-D-glucopyranoside(6).结论所有化合物均为首次从该种植物中分离纯化得到.
목적연구대협탁오적화학성분.방법응용다충색보방법화색보재료진행제취、분리화순화,용각충현대광보방법해석결구.결과종대협탁오근경적을순제취물중분리순화도사개황동순감화량개단첩감,분별위갑기서리소-3-O-β-D-예향당감(1),서리소-3-O-β-D-예향당감(2),호정(3),아복두감(4),화목감(5)화3,7-dimethyloct-1-en-3,8-diol-8-O-β-D-glucopyranoside(6).결론소유화합물균위수차종해충식물중분리순화득도.
OBJECTIVE To investigate the chemical constituents of the roots and rhizomes of Ligularia macrophylla.METHODS The compounds were isolated through repeated column chromatography on silica gel, polyamide, RP-18 and Sephadex LH-20. And the structures were elucidated on the basis of spectroscopic data (UV, IR, MS, 1H NMR, 13C NMR, DEPT and 2D NMR). RESULTS Four flavonol glycosides and two monoterpene glycosides were obtained and determined as rhamnazin-3-O-β-D-rutinoside ( 1 ), rhamnetin-3-O-β-D-rutinoside ( 2), rutin ( 3), afzelin ( 4), betulalbuside A (5) and 3,7-dimethyloct-1 -en-3,8-diol8-O-β-D- glucopyranoside (6). CONCLUSION All the compounds were isolated from this plant for the first time.