热带海洋学报
熱帶海洋學報
열대해양학보
JOURNAL OF TROPICAL OCEANOGRAPHY
2002年
1期
87-91
,共5页
戚穗坚%陈琪%彭文烈%徐安龙
慼穗堅%陳琪%彭文烈%徐安龍
척수견%진기%팽문렬%서안룡
软珊瑚Sinularia tenella Li%西松烯二萜内酯%细胞毒性
軟珊瑚Sinularia tenella Li%西鬆烯二萜內酯%細胞毒性
연산호Sinularia tenella Li%서송희이첩내지%세포독성
soft coral Sinularia tenella Li%cembrenolide diterpenoid%cytotoxicity
首次报道了柔弱短指软珊瑚Sinularia tenella Li的3个主要的西松烯二萜内酯:dihydroflexibilide(1),flexibilide(2)和sinulariolide(3)的分离和体外抗肿瘤活性.这3个化合物都显示出较强的抗肿瘤活性.
首次報道瞭柔弱短指軟珊瑚Sinularia tenella Li的3箇主要的西鬆烯二萜內酯:dihydroflexibilide(1),flexibilide(2)和sinulariolide(3)的分離和體外抗腫瘤活性.這3箇化閤物都顯示齣較彊的抗腫瘤活性.
수차보도료유약단지연산호Sinularia tenella Li적3개주요적서송희이첩내지:dihydroflexibilide(1),flexibilide(2)화sinulariolide(3)적분리화체외항종류활성.저3개화합물도현시출교강적항종류활성.
Dihydroflexibilide (1), flexibilide (2), sinulariolide (3), these three cembrenolide diterpenoids were isolated from marine soft coral Sinularia tenella Li for the first time. Their in vitro cytotoxicities on five human carcinoma cell lines were studied and reported for the first time. These three compounds all exhibited strong antitumor activities.
