CAJ | 학술논문

目的探讨胎儿期低水平铅暴露对新生儿神经、体格、听力发育的影响.方法收集235名孕妇所分娩新生儿脐带血各1 ml,采用石墨炉原子吸收光谱法测定脐带血中铅的含量;对新生儿出生体重、身长、头围进行测量,采用新生儿20项行为神经评分法检测神经行为;采用teoae方法对新生儿进行听力筛查.根据脐血铅水平,将研究对象分为低铅组、中铅组、高铅组3组,比较分析不同组别之间神经、体格、听力发育水平.结论胎儿期低水平铅暴露对新生儿神经行为发育有一定的影响,但未造成显著差异;对新生儿体格发育和听力发育亦未造成显著影响.结果胎儿期低水平铅暴露对新生儿神经行为发育有一定的影响,但较低浓度的血铅(本资料中脐血铅含量水平在0.048 3～0.463 8 μg/L,均数(15.67±0.077 2)μg/L,属于低浓度血铅)对胎儿体格发育、听力发育的影响尚未显著.结论妊娠期间采取有效预防措施减少铅暴露,使得分娩时脐带血血铅浓度保持在足够低的水平[(15.67±0.077 2)μg/L甚至更低],可以更好保障出生人口质量.
목적 탐토태인기저수평연폭로대신생인신경、체격、은력발육적영향.방법 수집235명잉부소분면신생인제대혈각1 ml,채용석묵로원자흡수광보법측정제대혈중연적함량;대신생인출생체중、신장、두위진행측량,채용신생인20항행위신경평분법검측신경행위;채용teoae방법 대신생인진행은력사사.근거제혈연수평,장연구대상분위저연조、중연조、고연조3조,비교분석불동조별지간신경、체격、은력발육수평.결론 태인기저수평연폭로대신생인신경행위발육유일정적영향,단미조성현저차이;대신생인체격발육화은력발육역미조성현저영향.결과 태인기저수평연폭로대신생인신경행위발육유일정적영향,단교저농도적혈연(본자료중제혈연함량수평재0.048 3～0.463 8 μg/L,균수(15.67±0.077 2)μg/L,속우저농도혈연)대태인체격발육、은력발육적영향상미현저.결론 임신기간채취유효예방조시감소연폭로,사득분면시제대혈혈연농도보지재족구저적수평[(15.67±0.077 2)μg/L심지경저],가이경호보장출생인구질량.
Objective To investigate the prenatal low-level lead exposure neonatal nerve, physical,hearing and development impact. Methods 235 pregnant women in the delivery of umbilical cord blood of 1mL, using graphite furnace atomic absorption spectrometry determination of lead content in umbilical cord blood; on neonatal birth weight, length, head circumference measurements, using 20 neonatal behavioral neurological assessment Detection of neural behavior; teoae methods used to conduct hearing screening for newborns. According to umbilical cord blood lead levels, will study the subjects were divided into low-lead group, in the lead group, the high lead group 3 group, a comparative analysis between the different groups of nerves, physical, hearing and development level. Conclusion prenatal low-level lead exposure on neonatal neurobehavioral development have an adverse effect, but did not result in significant differences; on neonatal physical development and hearing development did not cause significant impact.