CAJ | 학술논문

目的了解KISS-1在正常子宫内膜及子宫内膜异位症患者异位内膜组织中的表达关系.方法采用免疫组织化学EliVision plus技术,检测46例患者异位子宫内膜组织,55例正常子宫内膜组织中KISS-1的表达情况,对两组间表达情况进行比较.结果 KISS-1在子宫内膜异位症患者异位内膜及正常子宫内膜组织中阳性表达率分别为30.43%和63.64%,差异有统计学意义(P<0.01,P<0.05).结论 KISS-1在子宫内膜异位症中的表达减弱可能与内异症的发病有关.
목적 료해KISS-1재정상자궁내막급자궁내막이위증환자이위내막조직중적표체관계.방법 채용면역조직화학EliVision plus기술,검측46례환자이위자궁내막조직,55례정상자궁내막조직중KISS-1적표체정황,대량조간표체정황진행비교.결과 KISS-1재자궁내막이위증환자이위내막급정상자궁내막조직중양성표체솔분별위30.43%화63.64%,차이유통계학의의(P<0.01,P<0.05).결론 KISS-1재자궁내막이위증중적표체감약가능여내이증적발병유관.
Objective To study the expression of KISS-1 in normal endometrium and in ectopic endometri-um patients with endometriosis. Methods The expression of KISS-1 in 55 cases of normal endometrium as well in 46 cases of ectopie endometriurn with endometriosis were detected by immunohistochemicai EliVision plus method. Results The positive expression rates of KISS-1 in ectopic endometriotic tissues and in normal endometri-urn were 30.43 % and 63.64 % respectively ,and the positive expression rates in ectopic endometriotic tissues signifi-cantly lower than those in the normal endometrium( P< 0.01, P < 0.05). Conclusion The decreased expression of KISS-1 may be related to the mechanism of endometriosis.