CAJ | 학술논문

长片段的非编码RNA开始受到人们的关注,像mRNA-样通常由RNA聚合酶Ⅱ生成,但缺乏有意义的开放阅读框.它们直接作为不编码蛋白质的RNA发挥功能作用,并且部分长片段的非编码RNA已被证明作为基因调控子或调节核糖核酸发挥作用.近年来研究发现,某些长片段的非编码RNA与某些肿瘤的发生、发展密切相关.
장편단적비편마RNA개시수도인문적관주,상mRNA-양통상유RNA취합매Ⅱ생성,단결핍유의의적개방열독광.타문직접작위불편마단백질적RNA발휘공능작용,병차부분장편단적비편마RNA이피증명작위기인조공자혹조절핵당핵산발휘작용.근년래연구발현,모사장편단적비편마RNA여모사종류적발생、발전밀절상관.
A class of noncoding RNAs (ncRNAs) that have received increasing attentions are the long ncRNAs that, like mRNAs, are usually produced by RNA polymerase Ⅱ, but lack significant open reading frames. They appear to exert functional roles directly as ncRNAs and some have been identified to function as genetic regulators or riboregulators. Some researches in recent years suggest that some of them correlate with the tumorigenesis and tumor development.