中华风湿病学杂志
中華風濕病學雜誌
중화풍습병학잡지
CHINESE JOURNAL OF RHEUMATOLOGY
2011年
3期
155-158
,共4页
徐建伟%翟屹%殷召雪%施小明%柳玉芝%曾毅
徐建偉%翟屹%慇召雪%施小明%柳玉芝%曾毅
서건위%적흘%은소설%시소명%류옥지%증의
高尿酸血症%患病率%危险因素
高尿痠血癥%患病率%危險因素
고뇨산혈증%환병솔%위험인소
Hyperuricemia%Prevalence%Risk factors
目的 调查我国长寿地区中老年人群高尿酸血症的患病情况,并对其相关危险因素进行分析.方法 选取7个中国长寿之乡的所有百岁老人以及在该地区随机选取的40~、60~、80~和90~岁人群为研究对象,进行高尿酸血症及相关危险因素的问卷调查,体格检查和血、尿检测,采用非条件Logistic 回归分析高尿酸血症的影响因素.结果 男性中百岁老人高尿酸血症患病率最高为12.73%,女性中90~岁组高尿酸血症患病率最高为18.75%,高尿酸血症组的高血压、糖尿病、肾功能下降、高胆固醇血症、高甘油三酯血症、高低密度脂蛋白血症的患病率明显升高,多因素Logistic回归分析提示肾功能下降、高甘油三酯血症、高低密度脂蛋白血症、血尿素氮升高、饮酒为高尿酸血症的危险因素.结论 我国长寿地区中老年人群中90岁以上高龄老人的高尿酸血症患病率较高,提示对于老年高尿酸血症患者的治疗应采取综合防治的措施.
目的 調查我國長壽地區中老年人群高尿痠血癥的患病情況,併對其相關危險因素進行分析.方法 選取7箇中國長壽之鄉的所有百歲老人以及在該地區隨機選取的40~、60~、80~和90~歲人群為研究對象,進行高尿痠血癥及相關危險因素的問捲調查,體格檢查和血、尿檢測,採用非條件Logistic 迴歸分析高尿痠血癥的影響因素.結果 男性中百歲老人高尿痠血癥患病率最高為12.73%,女性中90~歲組高尿痠血癥患病率最高為18.75%,高尿痠血癥組的高血壓、糖尿病、腎功能下降、高膽固醇血癥、高甘油三酯血癥、高低密度脂蛋白血癥的患病率明顯升高,多因素Logistic迴歸分析提示腎功能下降、高甘油三酯血癥、高低密度脂蛋白血癥、血尿素氮升高、飲酒為高尿痠血癥的危險因素.結論 我國長壽地區中老年人群中90歲以上高齡老人的高尿痠血癥患病率較高,提示對于老年高尿痠血癥患者的治療應採取綜閤防治的措施.
목적 조사아국장수지구중노년인군고뇨산혈증적환병정황,병대기상관위험인소진행분석.방법 선취7개중국장수지향적소유백세노인이급재해지구수궤선취적40~、60~、80~화90~세인군위연구대상,진행고뇨산혈증급상관위험인소적문권조사,체격검사화혈、뇨검측,채용비조건Logistic 회귀분석고뇨산혈증적영향인소.결과 남성중백세노인고뇨산혈증환병솔최고위12.73%,녀성중90~세조고뇨산혈증환병솔최고위18.75%,고뇨산혈증조적고혈압、당뇨병、신공능하강、고담고순혈증、고감유삼지혈증、고저밀도지단백혈증적환병솔명현승고,다인소Logistic회귀분석제시신공능하강、고감유삼지혈증、고저밀도지단백혈증、혈뇨소담승고、음주위고뇨산혈증적위험인소.결론 아국장수지구중노년인군중90세이상고령노인적고뇨산혈증환병솔교고,제시대우노년고뇨산혈증환자적치료응채취종합방치적조시.
Objective To describe the prevalence of hyperuricemia of centenarians in longevity areas of China and the risk factors were analyzed. Methods All centenarians in 7 longevity areas were selected,and people aged 40 ~, 60 ~, 80 ~ and 90 ~ were selected randomly in the same 7 areas. The data of demographic data, dieting habits and diseases history were collected by questionnaire survey. Hyperuricemia and associated risk factors, physical examination and biochemical tests were collected. Logistic regression was used to analyze the hypemricemia and its relevant factors. Results The highest prevalence of hyperuricemia was found in centenarian men, which was 12.73%, the highest prevalence of hyperuricemia among 90~ women was 18.75%. The hyperuricemia group were more prone to have hypertension, diabetes, renal function decreased, hypercholesterolemia, hypertriglyceridemia, high density lipoprotein. Logistic regression analysis showed that renal function declined, high TG, high density lipoprotein hyperlipidemia, blood urea nitrogen increased, drinking were risk factors for hyperuricemia. Conclusion The prevalence of hyperuricemia in people older than 90 years and above in longevity areas is high. The results suggest that the treatment strategy for hyperuricemia should be a comprehensive one that combines preventive measures with medication interventions.