CAJ | 학술논문

目的研究并客观评价开放性颅骨缺损急诊术中一次完成自体修复的可行性。方法对17例开放性颅骨骨折病例(伤后24小时内)常规清创处理，同时将创伤区粉碎之颅骨用骨钳咬碎成3～5mm颗粒，与制备好的脱钙人牙基质2～6g均匀混合，平铺在颅骨缺损区的硬脑膜上，覆盖头皮，分层缝合。结果全部病例骨缺损区于术后1个月逐渐骨化，触之变硬，与周围骨窗融合良好。X线片见骨窗区骨碎粒逐渐融合，缺损区普遍密度增高。结论对开放性颅骨缺损在急诊清创的同时，使用脱钙人牙基质诱导缺损颅骨自体修复是对传统治疗方法的一种突破。
목적연구병객관평개개방성로골결손급진술중일차완성자체수복적가행성。방법대17례개방성로골골절병례(상후24소시내)상규청창처리，동시장창상구분쇄지로골용골겸교쇄성3～5mm과립，여제비호적탈개인아기질2～6g균균혼합，평포재로골결손구적경뇌막상，복개두피，분층봉합。결과전부병례골결손구우술후1개월축점골화，촉지변경，여주위골창융합량호。X선편견골창구골쇄립축점융합，결손구보편밀도증고。결론대개방성로골결손재급진청창적동시，사용탈개인아기질유도결손로골자체수복시대전통치료방법적일충돌파。
Objective　To research and evaluate the possibility of autogenous repairing.Methods　Seventeen cases of open skull fracture were selected(8 cases of 3-4cm defective area,6 cases of 5-6cm and 3 cases of 7-8cm),under only one routine debriedement all cases were used with DHDM 2-6g according to the range of defective area and mixed with smashed bone pieces grinding into 3-5mm in diameter,scattered it on the dure mater surface then skin flap was overlapped and sutured in layers.Results　All cases of defective area had gradual osteogensis after 1 month,rigidness of touching on the surface,the bone window margin and defective area were fused very well.X-ray film showed the bone pieces of bone window were fused gradually,the density of defective area increased generally.Conclusion　This study demonstrates that DHDM can induce autogenous repairing of skull defect during the debriedement was performed.It is a break throw of traditional therapeutic method.The curative effect is reliable.