CAJ | 학술논문

目的探讨手术治疗精索静脉曲张(VC)对患者血清中抗精子抗体(ASAB)的影响.方法分析60例左侧Ⅱ.VC患者.20例作为观察对照(A组);20例行保留睾丸动脉的精索静脉高位结扎术(B组);20例行不保留睾丸动脉的精索静脉高位结扎术(C组).酶联免疫法定量测定血清中抗精子抗体IgG、IgM含量.SPSS16.0软件进行统计学分析.结果三组术前IgM、IgG总体比较无统计学意义(F=0.59,p=0.5583;F=0.98,p=0.3808),术前IgM、IgG各组间两两比较均亦无统计学差异;三组术后IgM、IgG总体比较有统计学意义(F=29.47,p＜0.001;F=30.45,P＜0.001),且术后IgM、IgG各组间两两比较均有统计学意义,其中B组与C组IgM、IgG比较均有统计学意义(Q=3.1357,p＜0.05;Q=3.1733,P＜0.05).A组前后ASAB水平变化无统计学意义(p＞0.05).B.C两组术前术后ASAB水平差异均有显著性意义(p＜0.01).结论左侧Ⅱ.VC患者经腹腔镜手术治疗后血清中ASAB水平降低,且保留睾丸动脉效果更佳.
목적 탐토수술치료정색정맥곡장(VC)대환자혈청중항정자항체(ASAB)적영향.방법 분석60례좌측Ⅱ.VC환자.20례작위관찰대조(A조);20례행보류고환동맥적정색정맥고위결찰술(B조);20례행불보류고환동맥적정색정맥고위결찰술(C조).매련면역법정량측정혈청중항정자항체IgG、IgM함량.SPSS16.0연건진행통계학분석.결과 삼조술전IgM、IgG총체비교무통계학의의(F=0.59,p=0.5583;F=0.98,p=0.3808),술전IgM、IgG각조간량량비교균역무통계학차이;삼조술후IgM、IgG총체비교유통계학의의(F=29.47,p＜0.001;F=30.45,P＜0.001),차술후IgM、IgG각조간량량비교균유통계학의의,기중B조여C조IgM、IgG비교균유통계학의의(Q=3.1357,p＜0.05;Q=3.1733,P＜0.05).A조전후ASAB수평변화무통계학의의(p＞0.05).B.C량조술전술후ASAB수평차이균유현저성의의(p＜0.01).결론 좌측Ⅱ.VC환자경복강경수술치료후혈청중ASAB수평강저,차보류고환동맥효과경가.
Objectives To investigate the level of anti-sperm antibodies ( ASAB ) in the serum of the patient with varicocele ( VC ) before and 3 ～ 9 months after surgery. Methods 60 cases of patients with Ⅱ° VC in left were chosen to measured serum ASAB in our study. 20 cases were observed as control group ( A group); 20 cases were reserved the testicular artery in surgery ( B group); 20 cases didnt preserved the testicular artery in surgery ( C group). The level of ASAB in the serum ( IgM and IgG) were performed before and 39 months after surgery,as measured by ELISA in a quantitative way. The data were analyzed by SPSS16.0 software. Results Before surgery, three groups of IgM, IgG were no statistically significant overall ( F = 0. 59, p = 0. 5583; F = 0. 98, p = 0. 3808 ),and there were no statistically significant between any 2 groups in IgM, IgG; After surgery, three groups of IgM, IgG overall comparison were statistically significant ( F =29.47, p ＜0.001 ;F =30.45, p ＜0.001 ), the differences between any 2 groups were statistically significant in IgM, IgG, In particular, the differences between B group and C group in IgM, IgG were statistically significant (Q = 3. 1357, p ＜ 0. 05; Q = 2.8271, p ＜ 0. 05 ). In A group, ASAB levels before surgery and after surgery showed no statistically significant (all p ＞0.05 ). In group B and C, preoperative and postoperative ASAB levels were differences, and the difference was statistically significant (all p ＜0.01 ). Conclusions Laparoscopic treatment ofⅡ°VC in left can decrease serum levels of ASAB ,and preserve the testicular artery is more effective.