CAJ | 학술논문

目的探讨儿童艾滋病的病因、临床特点和CD4计数的临床意义,为儿童艾滋病的控制提供依据. 方法回顾性分析2005年以来我院感染病科诊治的16例儿童艾滋病的临床资料. 结果 15例艾滋病患儿的父亲和(或)母亲有注射吸毒和(或)性乱史,l例病因不清.患儿临床表现多样,主要表现为发育迟缓(50.00%)和营养不良(43.75%)、发热(81.25%)、咳嗽(50.00%)、贫血、肝脾肿大等.2例患儿CD4计数在1000/mm3以上,但已出现肺部感染、贫血及发育迟缓症状;另外2例患儿CD4计数较低,抗病毒治疗1年余,未出现机会性感染表现.CD4计数经治疗均有所回升. 结论儿童艾滋病主要通过母婴垂直传播,临床症状重,预后差,患儿CD4计数大多下降,但其数值的高低和临床表现不相一致,因此应提高对其特点的认识,以利尽早诊断和治疗.
목적 탐토인동애자병적병인、림상특점화CD4계수적림상의의,위인동애자병적공제제공의거. 방법 회고성분석2005년이래아원감염병과진치적16례인동애자병적림상자료. 결과 15례애자병환인적부친화(혹)모친유주사흡독화(혹)성란사,l례병인불청.환인림상표현다양,주요표현위발육지완(50.00%)화영양불량(43.75%)、발열(81.25%)、해수(50.00%)、빈혈、간비종대등.2례환인CD4계수재1000/mm3이상,단이출현폐부감염、빈혈급발육지완증상;령외2례환인CD4계수교저,항병독치료1년여,미출현궤회성감염표현.CD4계수경치료균유소회승. 결론 인동애자병주요통과모영수직전파,림상증상중,예후차,환인CD4계수대다하강,단기수치적고저화림상표현불상일치,인차응제고대기특점적인식,이리진조진단화치료.
Objective To study the cause, clinical features and the CD4 counts significance in children with AIDS, so as to provide the basis for the control of child AIDS. Methods The data of 16 cases of child AIDS from January 2005 were retrospectively reviewed. Results The parents of 15 cases had the history of injecting drug use and (or) sexual promiscuity. The main clinical presentation in 16 cases were developmental delay(50.00%), malnutrition (43.75%), fever(81.25%), cough(50.00%), anemia and so on. There were pulmonary infection, anemia and developmental delay in 2 cases with CD4 counts ＞ 1000/mm~3. However, there were no opportunistic infections occurred in another 2 cases with low CD4 counts level during the treatment. The CD4 counts raised after the treatment in all cases.Conclusions The main transmission for child AIDS is matermal infant vertcal dissemination. The clinical symptom is severe and the prognosis is bad, CD4 counts decrease, but the counts do not consistent with the clinical manifestation,therefore, it is helpful to improve our awareness of the disease for early diagnosis and treatment.