CAJ | 학술논문

目的比较鼻咽癌调强放疗和常规放疗时肿瘤和正常组织受照剂量的差异.方法用CMS逆向治疗计划系统分别对30例T3N1M0鼻咽癌患者进行调强放疗和常规放疗计划设计,计算肿瘤和正常组织受照射剂量.结果调强放疗与常规放疗肿瘤所接受的剂量无明显差别(P＞0.05),射野内垂体和左右侧腮腺、颞叶、颞颌关节受照剂量低于常规放疗[(48.6±2.5)Gy比(62.5±4.8)Gy;(41.3±2.7)Gy比(67.7±2.6)Gy,(41.5±4.2)Gy比(66.0±2.7)Gy;(25.4±6.2)Gy比(56.3±1.4)Gy,(25.4±6.6)Gy比(56.1±1.5)Gy;(41.1±4.2)Gy比(62.5±5.9)Gy,(41.9±4.8)Gy比(60.1±10.0)Gy;P＜0.05].结论鼻咽癌调强放疗与常规放疗相比,肿瘤靶区剂量精确可靠,正常组织受照剂量得到有效控制.
목적 비교비인암조강방료화상규방료시종류화정상조직수조제량적차이.방법 용CMS역향치료계화계통분별대30례T3N1M0비인암환자진행조강방료화상규방료계화설계,계산종류화정상조직수조사제량.결과 조강방료여상규방료종류소접수적제량무명현차별(P＞0.05),사야내수체화좌우측시선、섭협、섭합관절수조제량저우상규방료[(48.6±2.5)Gy비(62.5±4.8)Gy;(41.3±2.7)Gy비(67.7±2.6)Gy,(41.5±4.2)Gy비(66.0±2.7)Gy;(25.4±6.2)Gy비(56.3±1.4)Gy,(25.4±6.6)Gy비(56.1±1.5)Gy;(41.1±4.2)Gy비(62.5±5.9)Gy,(41.9±4.8)Gy비(60.1±10.0)Gy;P＜0.05].결론 비인암조강방료여상규방료상비,종류파구제량정학가고,정상조직수조제량득도유효공제.
Objective To study and compare the dose difference of intensity modulated radiation therapy (IMRT) and conventional radiation therapy(CRT) affecting tumor and normal tissues. Methods Thirty nasopharyngeal carcinoma patients in stage T3N1M0 received IMRT and CRT with CMS system. The dose affecting tumor and normal tissues was calculated respectively. Results There was no significant difference of the dose between IMRT and CRT, but the dose affecting the normal tissue was lower in IMRT than that in CRT. Conclusions The dose distribution to tumor target area is more precise with IMRT than that with CRT. The dose to the normal tissues is controlled more effectively with IMRT than that with CRT.