中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2009年
6期
473-475
,共3页
鞠辉%刘希双%王光兰%张海燕%戴素美%毛涛
鞠輝%劉希雙%王光蘭%張海燕%戴素美%毛濤
국휘%류희쌍%왕광란%장해연%대소미%모도
肠易激综合征%肠道菌群%临床特点
腸易激綜閤徵%腸道菌群%臨床特點
장역격종합정%장도균군%림상특점
Irritable bowel syndrome%Intestinal mieroflora%Clinical characteristics
目的 调查分析青岛地区感染后肠易激综合征(PI-IBS)患者的临床特点.方法 收集门诊1BS患者,采用问卷调查方式,内容包括一般资料、症状和微生态制剂治疗前后的生活质量表.结果 (1)PI-IBS患者中女性患病率是男性的2.2倍,与非感染后肠易激综合征(non-PI-IBS)相近;(2)PI-IBS与non-PI-IBS患者都以脑力劳动者居多;(3)PI-IBS与non-PI-IBS患者的消化系统以外的伴随症状中,以躯体性不适为主的表现(疲劳、头痛、头晕、背痛等)的差异无统计学意义(X<'2>=10.5,P>0.05),而以精神性不适为主的表现(紧张、多疑、抑郁、焦虑等)PI-IBS要明显多于non-PI-IBS,差异有统计学意义(X<'2>=28.7,P<0.05);(4)PI-IBS的肠道菌群失调率明显高于non-PI-IBS患者;(5)PI-IBS患者在双歧三联活菌治疗1个月后,生活质最评分的差异有统计学意义(t=3.8,P<0.01),而non-PI-IBS患者治疗前后的差异无统计学意义(t=1.5,P>0.05).结论 青岛地区PI-IBS与non-PI-IBS的某些临床特点存在差异.
目的 調查分析青島地區感染後腸易激綜閤徵(PI-IBS)患者的臨床特點.方法 收集門診1BS患者,採用問捲調查方式,內容包括一般資料、癥狀和微生態製劑治療前後的生活質量錶.結果 (1)PI-IBS患者中女性患病率是男性的2.2倍,與非感染後腸易激綜閤徵(non-PI-IBS)相近;(2)PI-IBS與non-PI-IBS患者都以腦力勞動者居多;(3)PI-IBS與non-PI-IBS患者的消化繫統以外的伴隨癥狀中,以軀體性不適為主的錶現(疲勞、頭痛、頭暈、揹痛等)的差異無統計學意義(X<'2>=10.5,P>0.05),而以精神性不適為主的錶現(緊張、多疑、抑鬱、焦慮等)PI-IBS要明顯多于non-PI-IBS,差異有統計學意義(X<'2>=28.7,P<0.05);(4)PI-IBS的腸道菌群失調率明顯高于non-PI-IBS患者;(5)PI-IBS患者在雙歧三聯活菌治療1箇月後,生活質最評分的差異有統計學意義(t=3.8,P<0.01),而non-PI-IBS患者治療前後的差異無統計學意義(t=1.5,P>0.05).結論 青島地區PI-IBS與non-PI-IBS的某些臨床特點存在差異.
목적 조사분석청도지구감염후장역격종합정(PI-IBS)환자적림상특점.방법 수집문진1BS환자,채용문권조사방식,내용포괄일반자료、증상화미생태제제치료전후적생활질량표.결과 (1)PI-IBS환자중녀성환병솔시남성적2.2배,여비감염후장역격종합정(non-PI-IBS)상근;(2)PI-IBS여non-PI-IBS환자도이뇌력노동자거다;(3)PI-IBS여non-PI-IBS환자적소화계통이외적반수증상중,이구체성불괄위주적표현(피로、두통、두훈、배통등)적차이무통계학의의(X<'2>=10.5,P>0.05),이이정신성불괄위주적표현(긴장、다의、억욱、초필등)PI-IBS요명현다우non-PI-IBS,차이유통계학의의(X<'2>=28.7,P<0.05);(4)PI-IBS적장도균군실조솔명현고우non-PI-IBS환자;(5)PI-IBS환자재쌍기삼련활균치료1개월후,생활질최평분적차이유통계학의의(t=3.8,P<0.01),이non-PI-IBS환자치료전후적차이무통계학의의(t=1.5,P>0.05).결론 청도지구PI-IBS여non-PI-IBS적모사림상특점존재차이.
Objective To investigate the clinical characteristics of postinfectious irritable bowel syndrome (PI-IBS) in Qingdao. Methods Two hundred and four PI-IBS and 2068 non-PI-IBS patients were investigated with questionnaire including general information, symptoms and quality of life scores with microecological study before and after therapy. Results (1) The morbidity rate of PI-IBS in female was 2. times of that in male, which was similar to that in non-PI-IBS. (2) Brainwork labors dominated in both PI-IBS and non-Pl-lBS patients. (3) As to the simultaneous presence of extra-gastrointestinal symptoms,there was no statistical difference between the rate of physical symptoms in PI-IBS and non-PI-IBS patients (X<'2>= 10. 5, P>0.05) ,but the rate of mental symptoms was higher in PI-IBS than in non-PI-IBS patients, and the difference was significant(X<'2>= 28.7, P<0.05). (4)The alteration of intestinal microflora rate in PI-IBS was obviously higher than that in non-PI-IBS patients. (5) The quality of life scores in PI-IBS was improved after treatment with Birid Triple Viable , and there was significant difference(t =3. 8, P<0.01),but there was no statistical difference in non-Pl-IBS (t = 1.5, P>0.05). Conclusion There was some difference in certain clinical characteristics between PI-IBS and non-PI-IBS patients in Qingdao.