中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
10期
1034-1036
,共3页
低钠血症%垂体腺瘤%外科手术
低鈉血癥%垂體腺瘤%外科手術
저납혈증%수체선류%외과수술
Hyponatremia%Pituitary adenoma%Surgery
目的 评估垂体腺瘤术后低钠血症发生的相关因素及预后.方法 回顾性分析2008年1月至2010年12月期间收治的120例垂体腺瘤手术患者的临床资料,统计分析垂体腺瘤患者术后低钠血症的发生率及其与临床病理因素的相互关系并进行对症治疗.结果 120例垂体腺瘤患者术后出现低钠血症28例(23.3％),经治疗7例患者血钠浓度在3d内恢复正常,21例在4～7d恢复正常.低钠血症与患者年龄、肿瘤大小、类型、术后早期有无尿崩症有相关性(x2 =12.6、12.4、5.38、6.51,P均＜0.05)；低钠血症与性别无关(P＞0.05).结论 垂体腺瘤术后低钠血症多见于垂体巨大腺瘤、年龄≥50岁及曾患尿崩症者,术后1～2周检测血电解质及补钠治疗有助于进一步干预和防止潜在严重并发症发生.
目的 評估垂體腺瘤術後低鈉血癥髮生的相關因素及預後.方法 迴顧性分析2008年1月至2010年12月期間收治的120例垂體腺瘤手術患者的臨床資料,統計分析垂體腺瘤患者術後低鈉血癥的髮生率及其與臨床病理因素的相互關繫併進行對癥治療.結果 120例垂體腺瘤患者術後齣現低鈉血癥28例(23.3％),經治療7例患者血鈉濃度在3d內恢複正常,21例在4～7d恢複正常.低鈉血癥與患者年齡、腫瘤大小、類型、術後早期有無尿崩癥有相關性(x2 =12.6、12.4、5.38、6.51,P均＜0.05)；低鈉血癥與性彆無關(P＞0.05).結論 垂體腺瘤術後低鈉血癥多見于垂體巨大腺瘤、年齡≥50歲及曾患尿崩癥者,術後1～2週檢測血電解質及補鈉治療有助于進一步榦預和防止潛在嚴重併髮癥髮生.
목적 평고수체선류술후저납혈증발생적상관인소급예후.방법 회고성분석2008년1월지2010년12월기간수치적120례수체선류수술환자적림상자료,통계분석수체선류환자술후저납혈증적발생솔급기여림상병리인소적상호관계병진행대증치료.결과 120례수체선류환자술후출현저납혈증28례(23.3％),경치료7례환자혈납농도재3d내회복정상,21례재4～7d회복정상.저납혈증여환자년령、종류대소、류형、술후조기유무뇨붕증유상관성(x2 =12.6、12.4、5.38、6.51,P균＜0.05)；저납혈증여성별무관(P＞0.05).결론 수체선류술후저납혈증다견우수체거대선류、년령≥50세급증환뇨붕증자,술후1～2주검측혈전해질급보납치료유조우진일보간예화방지잠재엄중병발증발생.
Objective To investigate the factors associated with hyponatremia after pituitary adenoma surgery and its prognosis.Methods Clinical data of 120 pituitary adenoma patients treated in our hospital form Jan.2008 to Dec.2010 were retrospectively collected.The incidence of hyponatremia after surgery,clinicopathology and related treatment were analyzed.Results In the 120 patients,28 (23.3％) occurred hyponatremia.The blood natrium concentration recovered to normal in 7 patients within 3 days,and in 21 patients within 4 -7 days.Hyponatremia was associated with age,size of adenoma,type and diabetes insipidus early after surgery(x2 =12.6,12.4,5.38 and 6.51,Ps ＜0.05).Conclusion Hyponatremia after pituitary adenoma surgery is frequent in patients with giant pituitary adenoma,history of diabetes insipidus and older than 50 yrs.Monitoring blood electrolyte and treatment with sodium in 1 - 2 weeks after surgery would be helpful to prevent potential severe compilations.
