CAJ | 학술논문

背景:随着人们寻求促进骨折愈合方法的同时,脉冲电磁场以其无创伤、无感染、治疗方便、副作用小等优点日益受到人们的关注与重视.目的:通过查阅大量相关资料并进行分析总结,从作用机制、动物实验和临床应用入手,对脉冲电磁场影响骨折愈合的研究现状进行综述,以期为促进骨折愈合提供新的思路和理论依据.方法:由第一作者检索Pubmed数据库(http://www.ncbi.nlm.gov/Pubmed)1989/2009及维普数据库(www.cqvip.com)1981/2009的相关文章.英文检索词为"PEMF,fracture",中文检索词为"脉冲电磁场,骨折".纳入与脉冲电磁场或电磁场治疗骨折密切相关,同一领域选择近期发表或在权威杂志上发表的文章;排除重复性文献.文献类型包括综述、动物试验和临床试验等.计算机初检得到62篇文献,英文32篇,中文30篇.阅读标题和摘要进行初筛,排除因研究目的与此文无关的9篇,内容重复性的研究6篇,综述、述评类7篇,保留40篇文献做进一步分析,包括16篇中文,24篇英文文献;其中动物实验和体内、体外、细胞学实验31篇,临床研究9篇.结果与结论:脉冲电磁场治疗骨折具有安全、环保、无创性、无感染、操作简便、适用范围广和并发症少等优点,动物实验和临床应用等证实脉冲电磁场是一种有效的促进骨折愈合的方法,目前公认的是要应用低频率、低强度.脉冲电磁场治疗骨折,不仅涉及物理学,而且涉及医学等多个学科,由于对电磁方面研究进展,以及机体的复杂性及伦理方面问题,其作用机制以及脉冲电磁场参数值及各参数间该如何组合还有待进一步探索.
배경:수착인문심구촉진골절유합방법적동시,맥충전자장이기무창상、무감염、치료방편、부작용소등우점일익수도인문적관주여중시.목적:통과사열대량상관자료병진행분석총결,종작용궤제、동물실험화림상응용입수,대맥충전자장영향골절유합적연구현상진행종술,이기위촉진골절유합제공신적사로화이론의거.방법:유제일작자검색Pubmed수거고(http://www.ncbi.nlm.gov/Pubmed)1989/2009급유보수거고(www.cqvip.com)1981/2009적상관문장.영문검색사위"PEMF,fracture",중문검색사위"맥충전자장,골절".납입여맥충전자장혹전자장치료골절밀절상관,동일영역선택근기발표혹재권위잡지상발표적문장;배제중복성문헌.문헌류형포괄종술、동물시험화림상시험등.계산궤초검득도62편문헌,영문32편,중문30편.열독표제화적요진행초사,배제인연구목적여차문무관적9편,내용중복성적연구6편,종술、술평류7편,보류40편문헌주진일보분석,포괄16편중문,24편영문문헌;기중동물실험화체내、체외、세포학실험31편,림상연구9편.결과여결론:맥충전자장치료골절구유안전、배보、무창성、무감염、조작간편、괄용범위엄화병발증소등우점,동물실험화림상응용등증실맥충전자장시일충유효적촉진골절유합적방법,목전공인적시요응용저빈솔、저강도.맥충전자장치료골절,불부섭급물이학,이차섭급의학등다개학과,유우대전자방면연구진전,이급궤체적복잡성급윤리방면문제,기작용궤제이급맥충전자장삼수치급각삼수간해여하조합환유대진일보탐색.
BACKGROUND: Pulsed electromagnetic field attracts much attention due to its less trauma, infection, side effect, and simple application to promote bone fracture healing.OBJECTIVE: To review the effect of pulsed electromagnetic fields on bone fracture healing by mechanism, animal experiments, and clinical application so as to provide theoretical evidences for promoting bone fracture healing. METHODS: This study was retrieved by the first author with the key words of "PEMF and fracture" in both English (1989-2009)and Chinese (1981-2009) from Pubmed database (http://www.ncbi.nlm.gov/Pubmed) and Vip database (www.cqvip.com). Articles which were related with the effect of pulsed electromagnetic fields or electromagnetic field on bone fracture healing were included.The duplicated articles were excluded. The retrieval articles included reviews, animal experiments, and clinical experiments.Among 62 articles, 32 were in English and 30 in Chinese. Following the primary retrieval, 9 articles were excluded due to unrelated researching aim, 6 due to duplication, and 7 due to reviews. A total of 40 articles, 16 in Chinese and 24 in English, wereincluded in the final analysis, including animal and cytological experiments (n=31), and clinical studies (n=9).RESULTS AND CONCLUSION: Pulsed electromagnetic field characterized by security, environmental protection, non-trauma,non-infection, sample processing, wide applicability, and less complications for treating bone fracture healing. Clinical experiments and clinical application have proved that pulsed electromagnetic field was an effective method to promote bone fracture healing, characterizing by low frequency and intensity. The mechanism of pulsed electromagnetic field for promoting bone fracture healing involved in physics and medicine. With the research of electromagnetism, organic complexity, and ethics, the parameters of pulsed electromagnetic field need to be further studied.