CAJ | 학술논문

采用1%醋酸水溶液直接对收集主流烟气的剑桥滤片进行简单的超声萃取,过滤后的萃取液用LC-MS/MS ESI负离子模式进行分析.研究了主流烟气中6种简单酚类化合物的LC-MS/MS法的液相操作条件、质谱分析测定参数、仪器最低检测限值、回收率、重复性、定量分析曲线等,为卷烟主流烟气中酚类化合物的定量检测建立了一种快速分析新方法,该方法具有前处理简单、分析时间短、数据可靠和回收率高等特点.
채용1%작산수용액직접대수집주류연기적검교려편진행간단적초성췌취,과려후적췌취액용LC-MS/MS ESI부리자모식진행분석.연구료주류연기중6충간단분류화합물적LC-MS/MS법적액상조작조건、질보분석측정삼수、의기최저검측한치、회수솔、중복성、정량분석곡선등,위권연주류연기중분류화합물적정량검측건립료일충쾌속분석신방법,해방법구유전처리간단、분석시간단、수거가고화회수솔고등특점.
The mainstream cigarette smoke collected in the Cambridge filter pad was ultrasonic extracted by 1% acetic acid solution with no other pretreatment.The extract was filtered through a 0.45 μm membrane filter,and then was analyzed by LC-MS-MS system operated in electrospray negative ion mode.6 phenolic compounds in mainstream cigarette smoke were determined by optimizing the LC analysis conditions and MS parameters.The limit of quantification,recoveries,repeatability,and the quantitative analysis were obtained at the optimal analysis conditions.In conclusion,a new method of rapid quantitative determination of phenolic compounds in mainstream cigarette smoke has been established in this paper.The method has the features of simple pretreatment,rapid analysis,preciseness and credibility of the analysis.as well as high recoveries.