CAJ | 학술논문

采用涂布法,从胶州湾海泥样品中分离到224株放线菌菌株,并且从海水样品中分离到32株放线菌菌株.根据形态学特性,菌株被分成了7个组.同时利用杯碟法测定了它们的抗菌活性,其中约7%对金黄色葡萄球菌有活性,11%对八叠球菌有效,10%对大肠杆菌有效,11%对绿脓杆菌有效,2%对白色念珠菌有效,5%对隐球菌有效,6%对绿色产色链霉菌有效和6%对米赫毛霉有效.分离到的22%放线菌对所测定的病原微生物有抗性作用.我们的结果表明胶州湾放线菌能够产生对病原微生物有抗性作用的不同代谢物,这些代谢物可以作为筛选新颖天然产物的独特和丰富的资源.
채용도포법,종효주만해니양품중분리도224주방선균균주,병차종해수양품중분리도32주방선균균주.근거형태학특성,균주피분성료7개조.동시이용배설법측정료타문적항균활성,기중약7%대금황색포도구균유활성,11%대팔첩구균유효,10%대대장간균유효,11%대록농간균유효,2%대백색념주균유효,5%대은구균유효,6%대록색산색련매균유효화6%대미혁모매유효.분리도적22%방선균대소측정적병원미생물유항성작용.아문적결과표명효주만방선균능구산생대병원미생물유항성작용적불동대사물,저사대사물가이작위사선신영천연산물적독특화봉부적자원.
We isolated 224 actinomycetes strains from sea mud samples and 32 strains from seawater samples of the Jiaozhou Bay, China,by using the spread method. The isolates were grouped into 7 groups on basis of their morphological characteristics. Their antimicrobial activities were tested by using the cup-plate method, and the results showed that 7% of the isolates were active against Staphylococcus aureus, 11% against Sarcine lutea, 10% against Escherichia coli, 11% against Bacillus pyocyaneus, 2% against Candida albicans, 5% against Cryptococcus, 6% against Streptomyces viridochromogenes, and 6% against Mucor miehei. Twenty-two percent of isolates were active against at least one of the test organisms. Our data suggests that actinomycetes from the Jiaozhou Bay, China can produce various active metabolites against pathogenic microorganisms, which provids unique and plentiful sources to screen novel natural products for combating diseases in man.