CAJ | 학술논문

目的:比较正常人和原发性青光眼患者不同分区的多焦视觉诱发电位(multifocal visual evoked poten-tial,mfVEP),评价mfVEP在青光眼诊断中的作用.方法:采用法国Vision Monitor多焦视觉电生理仪的二阶kernel技术检测21例32只正常对照眼、37例58只原发性青光眼的mfVEP,将青光眼mfVEP振幅均方根(root mean square,RMS)及潜伏期与正常对照眼行不同分区的比较.结果:正常眼mfVEP的RMS值个体间变异大(变异系数CV=43.05%).青光眼mfVEP的RMS值在上下半视野,鼻上、颞上、鼻下、颞下四个象限及各个环形分区均较正常对照眼小,且在0～10°环形区域及鼻上象限差异有显著性意义(P＜0.05),二者各个区域的潜伏期无差异.结论:正常人mfVEP个体间变异性大;青光眼患者mfVEP振幅较正常人下降,且在中央区域及鼻上象限更为显著.
목적:비교정상인화원발성청광안환자불동분구적다초시각유발전위(multifocal visual evoked poten-tial,mfVEP),평개mfVEP재청광안진단중적작용.방법:채용법국Vision Monitor다초시각전생리의적이계kernel기술검측21례32지정상대조안、37례58지원발성청광안적mfVEP,장청광안mfVEP진폭균방근(root mean square,RMS)급잠복기여정상대조안행불동분구적비교.결과:정상안mfVEP적RMS치개체간변이대(변이계수CV=43.05%).청광안mfVEP적RMS치재상하반시야,비상、섭상、비하、섭하사개상한급각개배형분구균교정상대조안소,차재0～10°배형구역급비상상한차이유현저성의의(P＜0.05),이자각개구역적잠복기무차이.결론:정상인mfVEP개체간변이성대;청광안환자mfVEP진폭교정상인하강,차재중앙구역급비상상한경위현저.
AIM: To test the ability of multifocal visual evoked potential (mfVEP) in the detecting of glaucoma by comparing the mfVEP recorded from normal subjects and glaucoma patients.METHODS: The mfVEP of 32 normal eyes (n =21) and of 58 eyes (n =37) with primary glaucoma were recorded with the Vision Monitor electrophysical apparatus by the second kernel analysis and to determine the correlation of the topographic location between them.RESULTS: There were significant variability (the coefficient of variation was 43.05%) in mfVEP RMS amplitude in the normal subjects; The RMS amplitude of eyes with glaucoma were smaller than that of the normal eyes and significantly statistical difference were found in the relatively center (namely the 0° -10° ring zone) and in superior nasal quadrant (P＜0.05) while there were no significantly statistical differences of the latency time between them.CONCLUSION: The normal subjects have large individual variability of mfVEP responses. The RMS amplitude of the mfVEP of glaucomatous eyes descends, especially in center zone and superior nasal quadrant.