工业卫生与职业病
工業衛生與職業病
공업위생여직업병
INDUSTRIAL HEALTH AND OCCUPATIONAL DISEASES
2001年
3期
140-143
,共4页
王守林%陈宇炼%陈海燕%徐莉春%曹晋柱%杜冰%王顶贤%施爱民%徐希平%王心如
王守林%陳宇煉%陳海燕%徐莉春%曹晉柱%杜冰%王頂賢%施愛民%徐希平%王心如
왕수림%진우련%진해연%서리춘%조진주%두빙%왕정현%시애민%서희평%왕심여
职业女工%不良妊娠结局%多因素分析
職業女工%不良妊娠結跼%多因素分析
직업녀공%불량임신결국%다인소분석
目的研究丙烯腈对雄性小鼠生殖功能影响。方法给雄性性成熟小鼠皮下注射3，6，9，12mg.kg-1体重丙烯腈5和35天，观察睾丸细胞染色体畸变率、精子质量相关指标、雄鼠生育力。结果染毒剂量达6mg.kg-1即可致雄鼠活精率、雌鼠妊娠率下降，精子畸形率、死胎率、胎吸收率升高，与阴性对照组比较差异有显著性(P＜0.05)；剂量达9，12mg.kg-1时，除精子计数外，各观察指标均与阴性对照组差异有显著性或非常显著性，并呈现明显的剂量反应或剂量效应关系。结论染毒丙烯腈6mg.kg-1及以上剂量可对雄性小鼠生殖功能产生损害作用。
目的研究丙烯腈對雄性小鼠生殖功能影響。方法給雄性性成熟小鼠皮下註射3，6，9，12mg.kg-1體重丙烯腈5和35天，觀察睪汍細胞染色體畸變率、精子質量相關指標、雄鼠生育力。結果染毒劑量達6mg.kg-1即可緻雄鼠活精率、雌鼠妊娠率下降，精子畸形率、死胎率、胎吸收率升高，與陰性對照組比較差異有顯著性(P＜0.05)；劑量達9，12mg.kg-1時，除精子計數外，各觀察指標均與陰性對照組差異有顯著性或非常顯著性，併呈現明顯的劑量反應或劑量效應關繫。結論染毒丙烯腈6mg.kg-1及以上劑量可對雄性小鼠生殖功能產生損害作用。
목적연구병희정대웅성소서생식공능영향。방법급웅성성성숙소서피하주사3，6，9，12mg.kg-1체중병희정5화35천，관찰고환세포염색체기변솔、정자질량상관지표、웅서생육력。결과염독제량체6mg.kg-1즉가치웅서활정솔、자서임신솔하강，정자기형솔、사태솔、태흡수솔승고，여음성대조조비교차이유현저성(P＜0.05)；제량체9，12mg.kg-1시，제정자계수외，각관찰지표균여음성대조조차이유현저성혹비상현저성，병정현명현적제량반응혹제량효응관계。결론염독병희정6mg.kg-1급이상제량가대웅성소서생식공능산생손해작용。
Objective Hazardous factors on adverse pre gnancy outcomes among female workers were analyzed.Methods According to cur rent standards and methods,1 241 and1 208 occupational females married during 1992-1997 were simultaneously investigated in a large petrochemical corporation and a large fabric company.The factors affecting adverse pregnancy outcomes were evaluated by mono-factorial and multi-factorial non-conditional logistic regression analyses.Results and Conclusions The results suggest that hazardou s factors are artificial abortion,shift work,mixed benzene (benzene,toluene and xylene)exposure and alcohol drinking,of which the mixed benzene exposure could be used as an independent hazardous factor.
