CAJ | 학술논문

Objective To observe the effectiveness and side effects of GyneFix IN intrauterine device (IUD) in clinical useMaterials & methods The present study is a randomized clinical control trial, 1 956healthy parous women were randomly allocated into GyneFix IN group (n= 980) and ML Cu375 group (n= 976). Follow-up was arranged at 1, 3, 6 and 12 months after insertion. The discontinuation rates were calculated by using life table method.Results At the end of the first year, the pregnancy rate with IUDs and expulsion rate were 0. 4% and 2. 3% respectively in GyneFix IN group. It was the same as in ML Cu375 group (0. 4%, 2. 0%, P> 0. 05). The removal rate for medical reasons and the use-related discontinuation rate were 0. 4% and 3.1% respectively in GyneFix IN group, which were significantly lower than that in ML Cu375 group (1. 5%,4. 2%, P< 0. 01).Conclusion GyneFix IN IUD has high effectiveness, low expulsion rate and can significantly reduce the occurrence of side effects of bleeding and pain.