CAJ | 학술논문

目的：探讨子宫颈癌高剂量率192铱源腔内放射治疗的剂量与疗效、放疗副反应的关系。方法：68例子宫颈癌采用体外照射与Micro-Selectron高剂量率192铱后装机腔内照射治疗，由治疗计划系统制定个体化治疗方案，并按国际辐射剂量与测量委员会38号文件的建议，计算参考点和参考体积。结果：体外及腔内照射A点总剂量为65～72 Gy，B点53.8～60.2 Gy，膀胱和直肠参考点平均剂量分别为A点剂量的40.27％和57.68％，A点100％剂量水平的参考体积为98.39 cm3。结论：子宫颈癌的治疗效果与A点剂量有关，但不是惟一影响预后的因素，放射性膀胱炎、直肠炎的发生与膀胱、直肠的放射剂量有关。
목적：탐토자궁경암고제량솔192의원강내방사치료적제량여료효、방료부반응적관계。방법：68례자궁경암채용체외조사여Micro-Selectron고제량솔192의후장궤강내조사치료，유치료계화계통제정개체화치료방안，병안국제복사제량여측량위원회38호문건적건의，계산삼고점화삼고체적。결과：체외급강내조사A점총제량위65～72 Gy，B점53.8～60.2 Gy，방광화직장삼고점평균제량분별위A점제량적40.27％화57.68％，A점100％제량수평적삼고체적위98.39 cm3。결론：자궁경암적치료효과여A점제량유관，단불시유일영향예후적인소，방사성방광염、직장염적발생여방광、직장적방사제량유관。
Objective To explore the relationship between the dose of high dose rate192source intracavitary ra-diotherapy in cervical cancer and the clinical results and the side effect of radiotherapy. Methods 68 patientswith cervical cancer were treated by combined external with intracavitary radiotherapy. The intracavitary thera-py was delivered by Micro-Selectron high dose rate afterloading unit containing~iridium source. Before thetreatment the individual treatment scheme was formulated for every patient and the absorbed dose at referencepoints and reference volume were calculated according to the method recommended by ICRU report (No 38).Results The total dose at point A and B were 65 - 72 Gy and 53.8 - 60.2 Gy, respectively. In the intracavi-tary therapy the mean doses of bladder and rectal reference point were 40.27 % and 57.68 %, respectively. Themean reference volume was 98.39 cm3 at the 100% dose level of point A. Conclusions The clinical results ofcervical cancer was correlated with the dose of point A. The delayed reactions of urinary bladder and rectumwere correlated with the dose of irradiation.