CAJ | 학술논문

目的:观察瑞格列奈降低2型糖尿病人的空腹血糖,餐后2h血糖的作用.方法:2型糖尿病人68例,随机分为治疗组34例(男18,女16)及对照组34例(男17,女17).采用瑞格列奈0.5mg po tid×4周. 结果:能有效降低2型糖尿病人的空腹血糖,餐后2h血糖的作用 .有非常显著性差异(P<0.01),尚能降低糖化血红蛋白(P<0.01).结论:瑞格列奈能有效降低2型糖尿病人的空腹血糖,餐后2h血糖,降低血脂及糖化血红蛋白,且无明显副作用.
목적:관찰서격렬내강저2형당뇨병인적공복혈당,찬후2h혈당적작용.방법:2형당뇨병인68례,수궤분위치료조34례(남18,녀16)급대조조34례(남17,녀17).채용서격렬내0.5mg po tid×4주. 결과:능유효강저2형당뇨병인적공복혈당,찬후2h혈당적작용 .유비상현저성차이(P<0.01),상능강저당화혈홍단백(P<0.01).결론:서격렬내능유효강저2형당뇨병인적공복혈당,찬후2h혈당,강저혈지급당화혈홍단백,차무명현부작용.
OBJECTIVE:To evaluate the therapeu tic effectiveness of repaglinide in lowering the FBG and PPBG in type 2 diabetes among 68 patients.METHODS:68 cases were divided at random into two groups:Repaglinide group(34 patients, 17female, 17male) and Placebo-controlled gr oup(34 patients,16female and 18male).0.5mg repaglinide was taken orally before e ach meal in therapeutic group for 4 weeks,while the cases in control were treate d by placebo.RESULTS:Repaglinide could effectively decrease the leve ls of FBG,PPBG and HbA1C with significant difference when compare with the place bo(P<0.01).At the meantime,it could also lower the Cholesterol and triglyceride levels when compared with the control group(P<0.01).CO NCLUSION:Repaglinide was effective in lowering the levels of FBG,PPBG and HbA1C in type 2 diabetes patients without obvious side effects.