生物信息学
生物信息學
생물신식학
BIOINFORMATICS
2010年
1期
57-59,67
,共4页
降钙素基因相关肽%偏头痛%机制
降鈣素基因相關肽%偏頭痛%機製
강개소기인상관태%편두통%궤제
calcitonin gene-related peptide%migraine%pathogenesis
偏头痛是临床上常见的多发性疾病,主要表现为一侧或双侧头部反复发作的搏动性疼痛,可伴有恶心、呕吐、视物异常等神经症状.关于偏头痛的发病机制研究尚无定论.偏头痛的发病机理一直受到人们的关注,近年来一些研究表明,偏头痛的发作与头颅血管周围组织产生的血管活性物质,特别是与三叉神经血管系统的降钙素基因相关肽(calcitonin gene-related peptide,CGRP)的含量变化关系密切.
偏頭痛是臨床上常見的多髮性疾病,主要錶現為一側或雙側頭部反複髮作的搏動性疼痛,可伴有噁心、嘔吐、視物異常等神經癥狀.關于偏頭痛的髮病機製研究尚無定論.偏頭痛的髮病機理一直受到人們的關註,近年來一些研究錶明,偏頭痛的髮作與頭顱血管週圍組織產生的血管活性物質,特彆是與三扠神經血管繫統的降鈣素基因相關肽(calcitonin gene-related peptide,CGRP)的含量變化關繫密切.
편두통시림상상상견적다발성질병,주요표현위일측혹쌍측두부반복발작적박동성동통,가반유악심、구토、시물이상등신경증상.관우편두통적발병궤제연구상무정론.편두통적발병궤리일직수도인문적관주,근년래일사연구표명,편두통적발작여두로혈관주위조직산생적혈관활성물질,특별시여삼차신경혈관계통적강개소기인상관태(calcitonin gene-related peptide,CGRP)적함량변화관계밀절.
Migraine is a common,multiple episodic neurovascular disorder.Its attacks are characterized by an intense, throbbing and pulsatile headache, which is often unilateral or bilateral in onset and is accompanied by nausea, vomiting, photophobia and/or phonophobia.The understanding of migraine pathogenesis is still argument. The pathogenesis of migraine has been researched for many years .Some studies show that migraine attacks has closely related to the inflammation substance which is released by perivascular tissue in the cranium region, especially the changes of calcitonin gene-related peptide in the trigeminal nerve vascular system.