中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2012年
3期
279-281
,共3页
血浆置换%高脂血症%急性胰腺炎
血漿置換%高脂血癥%急性胰腺炎
혈장치환%고지혈증%급성이선염
Plasmapheresis%Hyperlipidemia%Acute pancreatitis
目的 探讨血浆置换治疗高脂血症性急性胰腺炎的临床效果.方法 回顾性分析24例高脂血症性急性胰腺炎患者的临床资料,使用常规治疗合并血浆置换治疗,比较分析血浆置换治疗前后患者临床症状、血脂(甘油三酯、胆固醇)浓度变化以及患者预后等.结果 24例患者中1例手术后行血浆置换治疗,1例极重症血浆置换治疗后再行手术治疗,余22例未行手术治疗.24例患者经血浆置换治疗后症状均有减轻、血脂浓度明显下降,甘油三酯从治疗前(24.55±10.76) mmol/L降到治疗后(3.85±3.02) mmol/L,差异有统计学意义(t=7.099,P＜0.01)；胆固醇从治疗前(10.82±5.06) mmol/L降到治疗后(3.43±1.28) mmol/L,差异有统计学意义(t=5.826,P＜0.01).24例均治愈出院.结论 血浆置换治疗高脂血症性急性胰腺炎安全、有效.
目的 探討血漿置換治療高脂血癥性急性胰腺炎的臨床效果.方法 迴顧性分析24例高脂血癥性急性胰腺炎患者的臨床資料,使用常規治療閤併血漿置換治療,比較分析血漿置換治療前後患者臨床癥狀、血脂(甘油三酯、膽固醇)濃度變化以及患者預後等.結果 24例患者中1例手術後行血漿置換治療,1例極重癥血漿置換治療後再行手術治療,餘22例未行手術治療.24例患者經血漿置換治療後癥狀均有減輕、血脂濃度明顯下降,甘油三酯從治療前(24.55±10.76) mmol/L降到治療後(3.85±3.02) mmol/L,差異有統計學意義(t=7.099,P＜0.01)；膽固醇從治療前(10.82±5.06) mmol/L降到治療後(3.43±1.28) mmol/L,差異有統計學意義(t=5.826,P＜0.01).24例均治愈齣院.結論 血漿置換治療高脂血癥性急性胰腺炎安全、有效.
목적 탐토혈장치환치료고지혈증성급성이선염적림상효과.방법 회고성분석24례고지혈증성급성이선염환자적림상자료,사용상규치료합병혈장치환치료,비교분석혈장치환치료전후환자림상증상、혈지(감유삼지、담고순)농도변화이급환자예후등.결과 24례환자중1례수술후행혈장치환치료,1례겁중증혈장치환치료후재행수술치료,여22례미행수술치료.24례환자경혈장치환치료후증상균유감경、혈지농도명현하강,감유삼지종치료전(24.55±10.76) mmol/L강도치료후(3.85±3.02) mmol/L,차이유통계학의의(t=7.099,P＜0.01)；담고순종치료전(10.82±5.06) mmol/L강도치료후(3.43±1.28) mmol/L,차이유통계학의의(t=5.826,P＜0.01).24례균치유출원.결론 혈장치환치료고지혈증성급성이선염안전、유효.
Objective To investigate the clinical effect of plasmapheresis in the treatment of hyperlipidemic acute pancreatitis.Methods Twenty four patients with hyperlidemic acute pancreatitis were treated with plasmapheresis combined with the conventional therapeutic measures.The clinical symptoms,serum levels of lipids (triglycerides,cholesterol)and the prognosis of patients were observed and compared before and after the treatment of plasmpheresis.Results One case underwent plasmapheresis after surgery,one case with extremely severe symptoms underwent surgical treatment after plasmapheresis,twenty two cases didn't underwent surgical treatment.After the plasmapheresis treatment the clinical symptoms of twenty four patients were alleviated and the blood lipid levels decreased significantly.The triglyceride concentrations decreased significantly from(24.55 ± 10.76) mmol/L to ( 3.85 ± 3.02 ) mmol/L ( t =7.099,P ＜ 0.01 ) and the cholesterol concentrations decreased significantly from ( 10.82 ± 5.06 ) mmol/L to ( 3.43 ± 1.28 ) mnol/L ( t =5.826,P ＜0.01 ).Twenty four cases of patients were cured and discharged.Conclusion It is safe and effective of plasmapheresis in treatmeat of hyperlipidemic acute pancreatitis.
