CAJ | 학술논문

目的分析新生儿呼吸机相关性肺炎(VAP)发生的相关因素,为VAP的防治提供一定的理论依据.方法回顾分析2006年1月至2009年12月温州市第三人民医院NICU呼吸机治疗的145例危重新生儿的临床资料.结果 145例机械通气患儿中发生VAP 52例,发生率为35.86%,主要相关因素为胎龄、出生体质量、机械通气时间及再插管情况等,两组比较差异有统计学意义(P<0.05).病原菌主要为条件致病的革兰阴性杆菌.结论 VAP与胎龄、出生体质量、机械通气时间及再插管情况密切相关,规范应用呼吸机、加强无菌操作、选择有效抗生素,可以控制VAP的发生和发展.
목적 분석신생인호흡궤상관성폐염(VAP)발생적상관인소,위VAP적방치제공일정적이론의거.방법 회고분석2006년1월지2009년12월온주시제삼인민의원NICU호흡궤치료적145례위중신생인적림상자료.결과 145례궤계통기환인중발생VAP 52례,발생솔위35.86%,주요상관인소위태령、출생체질량、궤계통기시간급재삽관정황등,량조비교차이유통계학의의(P<0.05).병원균주요위조건치병적혁란음성간균.결론 VAP여태령、출생체질량、궤계통기시간급재삽관정황밀절상관,규범응용호흡궤、가강무균조작、선택유효항생소,가이공제VAP적발생화발전.
Objective To investigate the relevant factors of neonatal ventilator-associated pneumonia(VAP),and to provide a theoretical basis of prevention and treatment.Methods Retrospective analyed the clinical data of 145 critically ill neonates,who were treated with mechanical ventilator from Jan 2006 to Dec 2009 in the Third People′s Hospital of Wenzhou City,NICU.According to whether the neonates were occurred VAP,they were divided into two groups:VAP group(52 cases) and without VAP group(93 cases).Results Fifty-two out of the 145 neonates developed VAP.The incidence of VAP was 35.86%,the main relevent factors were the gestational ages,birth weights,the duration of mechanical ventilation and the times of intubation.There was significant difference between the two groups (P<0.05).The main pathogens were opportunistic bacteria,and mostly were G-bacilli.Conclusion The incidence of VAP has a close conclusion with the gestational ages,the birth weights,the duration of mechanical ventilation and the times of intubation.Regulate the use of breathing machine,strengthen aseptic operation,and select effective antibiotic can control the occurrence and development of VAP.