影像科学与光化学
影像科學與光化學
영상과학여광화학
IMAGING SCIENCE AND PHOTOCHEMISTRY
2010年
1期
1-9
,共9页
金咪咪%欧植泽%高云燕%郝萍%殷卫峰%刘丽华
金咪咪%歐植澤%高雲燕%郝萍%慇衛峰%劉麗華
금미미%구식택%고운연%학평%은위봉%류려화
竹红菌素%人血清白蛋白%静电相互作用%光诱导电子转移%荧光猝灭
竹紅菌素%人血清白蛋白%靜電相互作用%光誘導電子轉移%熒光猝滅
죽홍균소%인혈청백단백%정전상호작용%광유도전자전이%형광졸멸
hypocrellin%human serum albumin%electrostatic interaction%photoinduced electron transfer%fluorescence quenching
利用多种光谱方法研究了Mg~(2+)-HA, Y~(3+)-HA, La~(3+)-HA等竹红菌甲素金属离子配合物(M-HA)与人血清白蛋白(HSA)之间的相互作用. 结果表明在pH 7.4和5.0条件下M-HA能够与HSA形成1:1的复合物, 其结合常数均大于2×10~4 L/mol. 电子自旋共振和荧光猝灭实验表明HSA和M-HA在激发态条件下具有光诱导电子转移作用.
利用多種光譜方法研究瞭Mg~(2+)-HA, Y~(3+)-HA, La~(3+)-HA等竹紅菌甲素金屬離子配閤物(M-HA)與人血清白蛋白(HSA)之間的相互作用. 結果錶明在pH 7.4和5.0條件下M-HA能夠與HSA形成1:1的複閤物, 其結閤常數均大于2×10~4 L/mol. 電子自鏇共振和熒光猝滅實驗錶明HSA和M-HA在激髮態條件下具有光誘導電子轉移作用.
이용다충광보방법연구료Mg~(2+)-HA, Y~(3+)-HA, La~(3+)-HA등죽홍균갑소금속리자배합물(M-HA)여인혈청백단백(HSA)지간적상호작용. 결과표명재pH 7.4화5.0조건하M-HA능구여HSA형성1:1적복합물, 기결합상수균대우2×10~4 L/mol. 전자자선공진화형광졸멸실험표명HSA화M-HA재격발태조건하구유광유도전자전이작용.
Interaction of metal complexes of hypocrellin A (M-HA), such as Mg~(2+)-HA, Y~(3+)-HA, La~(3+)-HA with human serum albumin (HSA) is studied by complex with moderate association constants (>2×10~4 L/mol) at pH 7.4 and 5.0. Electron paramagnetic resonance (EPR) and fluorescence quenching experiments indicate that photoinduced electron transfer from HSA to M-HA may occur at excited state.
