国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
22期
2770-2772,2785
,共4页
依那普利%吲达帕胺%糖尿病合并高血压
依那普利%吲達帕胺%糖尿病閤併高血壓
의나보리%신체파알%당뇨병합병고혈압
Enalapril%Indapamide%Diabetic mellitus and hypertension
目的 观察依那普利与吲达帕胺联合治疗老年2型糖尿病合并高血压的临床疗效.方法 将99例确诊糖尿病合并高血压的患者随机分为治疗组和对照组,治疗组(50例)用依那普利加吲达帕胺治疗,对照组(49例)单用依那普利治疗.治疗12周比较治疗前后的降压效果、血浆内皮素-1及血清钾、降糖疗效.结果 治疗组的降压效果(82.0%)和降低血浆内皮素-1[(75.42±12.16)pg/ml]方面要优于对照组[65.3%,(99.09±13.31)pg/ml],但两组在血清钾和降糖方面无显著性差异(P＞0.05).结论 依那普利与吲达帕胺联用可作为治疗糖尿病合并高血压的一种较好的治疗方案.
目的 觀察依那普利與吲達帕胺聯閤治療老年2型糖尿病閤併高血壓的臨床療效.方法 將99例確診糖尿病閤併高血壓的患者隨機分為治療組和對照組,治療組(50例)用依那普利加吲達帕胺治療,對照組(49例)單用依那普利治療.治療12週比較治療前後的降壓效果、血漿內皮素-1及血清鉀、降糖療效.結果 治療組的降壓效果(82.0%)和降低血漿內皮素-1[(75.42±12.16)pg/ml]方麵要優于對照組[65.3%,(99.09±13.31)pg/ml],但兩組在血清鉀和降糖方麵無顯著性差異(P＞0.05).結論 依那普利與吲達帕胺聯用可作為治療糖尿病閤併高血壓的一種較好的治療方案.
목적 관찰의나보리여신체파알연합치료노년2형당뇨병합병고혈압적림상료효.방법 장99례학진당뇨병합병고혈압적환자수궤분위치료조화대조조,치료조(50례)용의나보리가신체파알치료,대조조(49례)단용의나보리치료.치료12주비교치료전후적강압효과、혈장내피소-1급혈청갑、강당료효.결과 치료조적강압효과(82.0%)화강저혈장내피소-1[(75.42±12.16)pg/ml]방면요우우대조조[65.3%,(99.09±13.31)pg/ml],단량조재혈청갑화강당방면무현저성차이(P＞0.05).결론 의나보리여신체파알련용가작위치료당뇨병합병고혈압적일충교호적치료방안.
Objective To study the clinincal effect of enalapril and indapamide in treatment of patients with hypertension and type 2 diabetes mellitus. Metlod Ninty nine patients were randomly divided into two groups:treatment group(enalapril and indapamide) and control group(enalapril),Two groups were all treated for 12weeks. Casual blood pressure,some biochemical parameters,such as ET-1,blood potassuim,blood glucose,were evaluated before and after treatment. Result treatment group (enalapril and indapamide)had better effects than control group (enalapril) in reducing blood pressure and ET-1,while it had no significant in the blood potassuim, blood glucose. Conclusion enalapril and indapamide could be an effective method to care patients with hypertension and type2 diabetes mellitus.
