CAJ | 학술논문

目的探讨结、直肠癌术中异硫蓝染色定位前哨淋巴结的可行性及其临床意义.方法对44例结直肠癌患者术中肿瘤周围注射异硫蓝,定位前哨淋巴结,手术结束后,对前哨淋巴结和其他淋巴结行苏木素-伊红染色.结果术中44例患者共检出前哨淋巴结114个,每例患者的前哨淋巴结为1-5个,平均(2.6 ±2.1)个,44例患者非前哨淋巴结共检出792个,每例患者的非前哨淋巴结为9-35个,平均(18.0±8.7)个,44例患者中有28例(64%)有淋巴结转移,16例(36%)无淋巴结转移.28例有淋巴结转移患者中26例(93%)有前哨淋巴结转移,2例(7%)无前哨淋巴结转移.结论结直肠癌术中异硫蓝染色定位前哨淋巴结准确性较高,具有较强的临床实用价值.
목적 탐토결、직장암술중이류람염색정위전초림파결적가행성급기림상의의.방법 대44례결직장암환자술중종류주위주사이류람,정위전초림파결,수술결속후,대전초림파결화기타림파결행소목소-이홍염색.결과 술중44례환자공검출전초림파결114개,매례환자적전초림파결위1-5개,평균(2.6 ±2.1)개,44례환자비전초림파결공검출792개,매례환자적비전초림파결위9-35개,평균(18.0±8.7)개,44례환자중유28례(64%)유림파결전이,16례(36%)무림파결전이.28례유림파결전이환자중26례(93%)유전초림파결전이,2례(7%)무전초림파결전이.결론 결직장암술중이류람염색정위전초림파결준학성교고,구유교강적림상실용개치.
Objective To study the feasibility of sentinel lymph node(SLN)mapping during operation and the clinical value of analyzing lymph node metastasis of colon cancer. Methods SLN was mapped during operation by isosulfan stain in 44 cases with colon cancer. All lymph nodes were checked by routine pathological technique, while SLNs were checked by serial sectioning pathologic technique and immunohistochemistry. Results Twenty-eight of 44 cases were showed SLN. A total of 114 SLNs was positively inspected in 44 cases. The SLNs count in each case was 1-5, (2.6±2.1)SLNs in average. Seven hundred and ninety-two non-SLNs were inspected in these 44 cases. The non-SLNs count in each case was 9-35 (18.0 ±8.7 in average). In these 44 cases, 28(64%)had lymphatic metastasis and 16 (36%) didnt. Twenty-six cases of the 28 who had lymphatic metastasis were inspected metastasis of SLNs. Conclusion The SLN mapping during operation is feasible and helpful to the positive finding rate of the metastatic lymph node of colon cancer.