CAJ | 학술논문

目的探讨双导丝聚力球囊预扩张较普通球囊能否降低小血管支架置入术围术期并发症及改善支架置入术远期预后.方法连续人选冠状动脉造影显示小血管病变(参考血管直径≤2.75 mm)需行冠状动脉介入治疗的患者300例,完全随机分成研究组和对照组,每组150例.研究组:双导丝聚力球囊预扩张后置入支架;对照组:普通球囊预扩张后置入支架.观察冠状动脉介入治疗即刻成功率、血管并发症发生率.9-12个月复查冠状动脉造影,观察靶病变再狭窄发生率,12个月内不良心血管事件(MACE)发生率.结果研究组与对照组冠状动脉介入治疗手术成功率分别为98.7％(148例)与94.7％(142例),手术并发症发生率分别为1.3％(2例)与5.3％(8例),组间差异有统计学意义(均P＜0.05).9～12个月复查冠状动脉造影,研究组和对照组的MACE发生率分别为3.4％ (5/148)和7.0％ (10/142),组间差异无统计学意义(P＞0.05).结论双导丝聚力球囊较普通球囊扩张可降低小血管支架置入术围术期手术并发症,并具有改善支架置人术远期预后的趋势.
목적 탐토쌍도사취력구낭예확장교보통구낭능부강저소혈관지가치입술위술기병발증급개선지가치입술원기예후.방법 련속인선관상동맥조영현시소혈관병변(삼고혈관직경≤2.75 mm)수행관상동맥개입치료적환자300례,완전수궤분성연구조화대조조,매조150례.연구조:쌍도사취력구낭예확장후치입지가;대조조:보통구낭예확장후치입지가.관찰관상동맥개입치료즉각성공솔、혈관병발증발생솔.9-12개월복사관상동맥조영,관찰파병변재협착발생솔,12개월내불양심혈관사건(MACE)발생솔.결과 연구조여대조조관상동맥개입치료수술성공솔분별위98.7％(148례)여94.7％(142례),수술병발증발생솔분별위1.3％(2례)여5.3％(8례),조간차이유통계학의의(균P＜0.05).9～12개월복사관상동맥조영,연구조화대조조적MACE발생솔분별위3.4％ (5/148)화7.0％ (10/142),조간차이무통계학의의(P＞0.05).결론 쌍도사취력구낭교보통구낭확장가강저소혈관지가치입술위술기수술병발증,병구유개선지가치인술원기예후적추세.
Objective To assess the effect of dual-wire focused force balloon predilation followed by drugeluting stent placement for lesions of small coronary arteries.Methods Through coronary angiography,300 consecutive patients with unstable angina(reference vessel ≤2.75 mm in diameter) were randomly assigned to experimental group(dual-wire focused force balloon predilation group) and control group(balloon predilation group).Restenosis at 9-12 month were followed up through angiography.Clinic improvement and major adverse cardiac event(MACE) at 1 year were assessed.Results Procedural success was achieved in 98.7％(148/150) of patients assigned to experimental group and in 94.7％(142/150) of patients assigned to control group(P ＜ 0.05).Vessels complications in these two groups were 1.3％(2/150) and 5.3％(8/150) respectively(P ＜ 0.05).Less patients in experimental group experienced major adverse cardiac event [ 5/148(3.4％) vs 10/142(7.0％),P ＞ 0.05 ].There was no statistical difference between these two groups regarding restenosis and MACE,but the procedural suecess rate and vessel complications were different.Conclusion Dual-wire focused force balloon predilation reduced the incidence of perioperatine complications and provided tendency of improving outcomes followed by drug-eluting stent placement in small vessels.