华西药学杂志
華西藥學雜誌
화서약학잡지
WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
2001年
2期
128，131
,共2页
HPLC%甲硝唑%注射液
HPLC%甲硝唑%註射液
HPLC%갑초서%주사액
目的：采用HPLC测定甲硝唑葡萄糖注射液中甲硝唑含量。方法：用ODS柱(3.9 mm×300 mm)，以甲醇-水(40∶60)为流动相，检测波长为310 nm。结果：在25～125 μg*ml-1范围内，甲硝唑峰面积与浓度呈良好线性关系，r=0.9999，平均回收率为99.90%，RSD为0.43%(n=6)。结论：该方法简便、准确可靠。
目的：採用HPLC測定甲硝唑葡萄糖註射液中甲硝唑含量。方法：用ODS柱(3.9 mm×300 mm)，以甲醇-水(40∶60)為流動相，檢測波長為310 nm。結果：在25～125 μg*ml-1範圍內，甲硝唑峰麵積與濃度呈良好線性關繫，r=0.9999，平均迴收率為99.90%，RSD為0.43%(n=6)。結論：該方法簡便、準確可靠。
목적：채용HPLC측정갑초서포도당주사액중갑초서함량。방법：용ODS주(3.9 mm×300 mm)，이갑순-수(40∶60)위류동상，검측파장위310 nm。결과：재25～125 μg*ml-1범위내，갑초서봉면적여농도정량호선성관계，r=0.9999，평균회수솔위99.90%，RSD위0.43%(n=6)。결론：해방법간편、준학가고。
OBJECTIVE:To establish an HPLC for determination of metronidazole in the metronidazole and glucose injection. METHODS:The column was μbondapak ODS， the mobile phase consisted of methanol-water(40∶60)，the detective wavelength was 310 nm.RESULTS:The recovery of metronidazole was 99.90%,RSD was 0.43%(n=6).The linear range was 25～125 μg*ml-1(r=0.9999).CONCLUSION:The method was simple and accurate.
