CAJ | 학술논문

多囊卵巢综合征(PCOS)是育龄妇女常见的内分泌失调性疾病.胰岛素抵抗是其发生、发展的重要病理生理机制.近年来,PCOS患者胰岛素抵抗具体的分子机制得到了深入研究,涉及胰岛素的分泌、代谢和各种脂肪因子等.本文即对PCOS患者胰岛素抵抗分子机制的研究进展作一综述.
다낭란소종합정(PCOS)시육령부녀상견적내분비실조성질병.이도소저항시기발생、발전적중요병리생리궤제.근년래,PCOS환자이도소저항구체적분자궤제득도료심입연구,섭급이도소적분비、대사화각충지방인자등.본문즉대PCOS환자이도소저항분자궤제적연구진전작일종술.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of women in reproductive age. Insulin resistance (IR) plays a key role in the development of PCOS. The secre-tion and metabolism of insulin and adipokines are related to the molecular mechanism of IR in PCOS. This re-view focuses on the recent progress of this aspect.