CAJ | 학술논문

目的探讨高原地区全身炎症反应综合征(SIRS)与急性胰腺炎合并高原红细胞增多症病情严重程度的关系.方法回顾性分析2006年9月至2009年9月收治的40例符合急性胰腺炎合并高原红细胞增多症诊断患者及同期40例急性胰腺炎非高原红细胞增多症患者的临床资料,依据诊断标准分为高原红细胞增多症组和非高原红细胞增多症组.并将高原红细胞增多症组依据慢性健康状况Ⅱ评分分为轻症组和重症组.对患者有无SIRS、符合SIRS诊断标准数、SIRS诊断指标及急性胰腺炎合并高原红细胞增多症患者病情严重程度与SIRS持续时间的关系进行比较分析.结果高原红细胞增多症组和非高原红细胞增多症组有无SIRS与符合2项SIRS诊断标准患者所占比例的差异有统计学意义(P＜0.05);两组间SIRS各项诊断标准例数的差异有统计学意义(P＜0.05);急性胰腺炎合并高原红细胞增多症和SIRS患者的病情严重程度与符合2～3项SIRS诊断标准患者所占比例的差异有统计学意义(P＜0.05);急性胰腺炎合并高原红细胞增多症患者病情越严重,SIRS持续时间越长.结论高原地区SIRS与急性胰腺炎合并高原红细胞增多症病情严重程度密切相关.
목적 탐토고원지구전신염증반응종합정(SIRS)여급성이선염합병고원홍세포증다증병정엄중정도적관계.방법 회고성분석2006년9월지2009년9월수치적40례부합급성이선염합병고원홍세포증다증진단환자급동기40례급성이선염비고원홍세포증다증환자적림상자료,의거진단표준분위고원홍세포증다증조화비고원홍세포증다증조.병장고원홍세포증다증조의거만성건강상황Ⅱ평분분위경증조화중증조.대환자유무SIRS、부합SIRS진단표준수、SIRS진단지표급급성이선염합병고원홍세포증다증환자병정엄중정도여SIRS지속시간적관계진행비교분석.결과 고원홍세포증다증조화비고원홍세포증다증조유무SIRS여부합2항SIRS진단표준환자소점비례적차이유통계학의의(P＜0.05);량조간SIRS각항진단표준례수적차이유통계학의의(P＜0.05);급성이선염합병고원홍세포증다증화SIRS환자적병정엄중정도여부합2～3항SIRS진단표준환자소점비례적차이유통계학의의(P＜0.05);급성이선염합병고원홍세포증다증환자병정월엄중,SIRS지속시간월장.결론 고원지구SIRS여급성이선염합병고원홍세포증다증병정엄중정도밀절상관.
Objective To explore the relationship between systemic inflammatory response syndrome ( SIRS) and severity of acute pancreatitis combined with plateau erythrocythemia in the high altitude. Methods A retrospective analysis on the clinical data which involved acute pancreatitis combined with plateau erythrocythemia( n =40) and without plateau erythrocythemia( n =40) admitted from September 2006 to September 2009 was conducted. According to the unified standards, these cases were divided into plateau erythrocythemia group and no plateau erythrocythemia group. The patients in plateau erythrocythemia group were further divided into severe group and mild group according to scores of APACHE Ⅱ. The data was analyzed according to the patient with (or without) SIRS, SIRS's standard indicators, diagnostic parameter and relation of severity and duration of SIRS in acute pancreatitis combined with plateau erythrocythemia. Results There was significantly discrepancy between plateau erythrocythemia group and no plateau erythrocythemia group not only in the incidence of patients who developed SIRS,but also in two items of patients fulfilling or not fulfilling diagnostic criteria of SIRS( P < 0. 05 ). There was significant statistical difference in three items of diagnostic parameter of SIRS between plateau erythrocythemia group and no plateau erythrocythemia group (P <0. 05). Significant difference in two and three diagnostic parameter was found on severity of SIRS in acute pancreatitis combined with plateau erythrocythemia (P <0. 05). The more severity acute pancreatitis combined with plateau erythrocythemia was, the longer duration of SIRS was. Conclusion SIRS is highly correlated with the severity of SIRS in acute pancreatitis combined with plateau erythrocythemia in the high altitude.