CAJ | 학술논문

实验观察蚕蛹蛋白多肽对小鼠的免疫调节作用.实验将蚕蛹蛋白多肽分为高、中、低剂量组,分别为5.0、1.7、0.6g/kg bw·d喂饲小鼠40d,观察小鼠免疫器官指数变化、迟发型变态反应(DTH)、抗体生成细胞数和碳廓清能力等4个实验项目.实验结果表明:与阴性对照组比较,蚕蛹蛋白多肽能显著增加小鼠胸腺指数,增加小鼠足跖肿胀度,增加小鼠抗体细胞生成数量,增加单核.巨噬细胞吞噬能力.说明蚕蛹蛋白多肽具有明显的免疫调节作用.
실험관찰잠용단백다태대소서적면역조절작용.실험장잠용단백다태분위고、중、저제량조,분별위5.0、1.7、0.6g/kg bw·d위사소서40d,관찰소서면역기관지수변화、지발형변태반응(DTH)、항체생성세포수화탄곽청능력등4개실험항목.실험결과표명:여음성대조조비교,잠용단백다태능현저증가소서흉선지수,증가소서족척종창도,증가소서항체세포생성수량,증가단핵.거서세포탄서능력.설명잠용단백다태구유명현적면역조절작용.
In order to investigate immunoregulation functions of pupa polypeptides, mice were randomly divided 3 groups and conducted to oral administration of pupa polypeptides at the doses of 5.0,1.7 g/kg·d and 0.6 g/kg·d for 40 days, respectively. Changes in immune organ index, delayed-type hypersensitivity (DTH), number of antibody-producing cells and carbon clearance capability were examined to evaluate immune functions. Results indicated that pupa polypeptides could significantly improve thymus index, promote plantar swelling, increase the generation of antibody-producing cells and enhance capability of monocyte-macrophage phagocytosis. Therefore, pupa polypeptides exhibited a significant effect on improvement of immune functions in mice.