国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
INTERNATIONAL JOURNAL OF IMMUNOLOGY
2008年
1期
8-9
,共2页
盛宇%石峰%刘俊才%李鹤玉
盛宇%石峰%劉俊纔%李鶴玉
성우%석봉%류준재%리학옥
甲真菌病%淋巴细胞亚群%流式细胞仪
甲真菌病%淋巴細胞亞群%流式細胞儀
갑진균병%림파세포아군%류식세포의
Onychooycosis%Lymphocytes subpopulations%Flow cytometry
目的 探讨甲真菌病患者外周血淋巴细胞免疫表型的情况.方法 应用流式细胞仪对24例甲真菌病患者及20例健康人的外周血淋巴细胞亚群和自然杀伤细胞进行测定与分析.结果 甲真菌患者外周血CD8+淋巴细胞明显高于健康对照组(P<0.05),而CD3+细胞,CD4+细胞,CD4+/CD8+、CD19+细胞、CD16+CD 56+细胞与对照组变化不明显.结论 甲真菌患者存在着一定程度的细胞免疫异常,以CD8+细胞介导的免疫反应占主要地位.
目的 探討甲真菌病患者外週血淋巴細胞免疫錶型的情況.方法 應用流式細胞儀對24例甲真菌病患者及20例健康人的外週血淋巴細胞亞群和自然殺傷細胞進行測定與分析.結果 甲真菌患者外週血CD8+淋巴細胞明顯高于健康對照組(P<0.05),而CD3+細胞,CD4+細胞,CD4+/CD8+、CD19+細胞、CD16+CD 56+細胞與對照組變化不明顯.結論 甲真菌患者存在著一定程度的細胞免疫異常,以CD8+細胞介導的免疫反應佔主要地位.
목적 탐토갑진균병환자외주혈림파세포면역표형적정황.방법 응용류식세포의대24례갑진균병환자급20례건강인적외주혈림파세포아군화자연살상세포진행측정여분석.결과 갑진균환자외주혈CD8+림파세포명현고우건강대조조(P<0.05),이CD3+세포,CD4+세포,CD4+/CD8+、CD19+세포、CD16+CD 56+세포여대조조변화불명현.결론 갑진균환자존재착일정정도적세포면역이상,이CD8+세포개도적면역반응점주요지위.
Objective To evaluate the immunological competence in peripheral blood of the patients with onychomycosis. Methods The lymphocyte subpopalations and natural killer cells in the peripheral blood of 24 patients and a control group of 20 individuals were analysed by flow cytometry. Results The percentage of suppressor CD8+ lymphocytes in the patients were significantly higher than that in the normal controls (P < 0.05 ). No statistically significant difference was obtained in the percentages of CD3+ lymphocytes,CD4+ lymphocytes, CD19+ lymphocytes, CD16+, CD56+ lymphocytes. Conclusion CD8+ lymphocytes plays an importand role in mediating the cell mediated immunity in onychomycosis.
