CAJ | 학술논문

某些过渡金属可催化亲电性不饱和碳与含活泼氢的氮、氧、硫、碳原子直接成键,这种交叉偶联反应是现代有机合成中重要的手段之一.与钯、镍等过渡金属相比,铜是一种廉价且毒性低的金属,用铜来催化这些交叉偶联反应不仅可以节省贵金属的消耗,降低成本,而且可以减少对环境的污染,促进绿色化学的发展.对铜催化碳杂键偶联反应的最新研究进展做了综述.
모사과도금속가최화친전성불포화탄여함활발경적담、양、류、탄원자직접성건,저충교차우련반응시현대유궤합성중중요적수단지일.여파、얼등과도금속상비,동시일충렴개차독성저적금속,용동래최화저사교차우련반응불부가이절성귀금속적소모,강저성본,이차가이감소대배경적오염,촉진록색화학적발전.대동최화탄잡건우련반응적최신연구진전주료종술.
The transition metal-catalyzed cross-coupling reaction to form sp~2 C-C or C-hetero atom bonds is one of the most important methods for modern organic synthesis.In comparison with Pd and Ni,copper is a cheap metal with low-toxicity.In this review the newest development of the Cu catalysts in C-N cross-coupling reactions is summarized.