中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2011年
7期
580-583
,共4页
江雪莲%施建元%张杉杉%顾雪明%周云飞%刘宏%方萍%汤正义%宁光
江雪蓮%施建元%張杉杉%顧雪明%週雲飛%劉宏%方萍%湯正義%寧光
강설련%시건원%장삼삼%고설명%주운비%류굉%방평%탕정의%저광
糖尿病足溃疡%心衰%左室射血分数
糖尿病足潰瘍%心衰%左室射血分數
당뇨병족궤양%심쇠%좌실사혈분수
Diabetic foot ulcer%Heart failure%Left ventricular ejection fraction
目的 观察糖尿病足溃疡患者心衰特点,探讨心功能随治疗的变化.方法 连续收集162例糖尿病足溃疡(足溃疡组)和75例糖尿病足溃疡高危患者足溃疡高危组一般临床资料,包括糖尿病病情、生理生化指标等,在入院时、治疗中和出院前评估患者心功能状态,通过心脏超声观察心脏左室射血分数等心功能指标.结果 本组资料中发生心衰共23.6%(56/237),其中足溃疡组27.2%(44/162),均为左室射血分数正常心功能不全.入院时总体患病率为8.9%(21/237),其中足部溃疡组10.5%(17/162),与足溃疡高危组相比差异有统计学意义(P＜0.01);在住院治疗期间,心衰新增加14.8%(35/237),其中足溃疡组为16.7%(27/162),均发生在治疗后2~7 d,高峰在治疗后第4天;治疗后发生的心衰在足溃疡Wagner分级各组间差异有统计学意义(P＜0.05);心衰经治疗后心功能均改善并能耐受足溃疡的治疗.结论 糖尿病足溃疡在治疗前和治疗中有较高的左室射血分数正常心功能不全患病率.
目的 觀察糖尿病足潰瘍患者心衰特點,探討心功能隨治療的變化.方法 連續收集162例糖尿病足潰瘍(足潰瘍組)和75例糖尿病足潰瘍高危患者足潰瘍高危組一般臨床資料,包括糖尿病病情、生理生化指標等,在入院時、治療中和齣院前評估患者心功能狀態,通過心髒超聲觀察心髒左室射血分數等心功能指標.結果 本組資料中髮生心衰共23.6%(56/237),其中足潰瘍組27.2%(44/162),均為左室射血分數正常心功能不全.入院時總體患病率為8.9%(21/237),其中足部潰瘍組10.5%(17/162),與足潰瘍高危組相比差異有統計學意義(P＜0.01);在住院治療期間,心衰新增加14.8%(35/237),其中足潰瘍組為16.7%(27/162),均髮生在治療後2~7 d,高峰在治療後第4天;治療後髮生的心衰在足潰瘍Wagner分級各組間差異有統計學意義(P＜0.05);心衰經治療後心功能均改善併能耐受足潰瘍的治療.結論 糖尿病足潰瘍在治療前和治療中有較高的左室射血分數正常心功能不全患病率.
목적 관찰당뇨병족궤양환자심쇠특점,탐토심공능수치료적변화.방법 련속수집162례당뇨병족궤양(족궤양조)화75례당뇨병족궤양고위환자족궤양고위조일반림상자료,포괄당뇨병병정、생리생화지표등,재입원시、치료중화출원전평고환자심공능상태,통과심장초성관찰심장좌실사혈분수등심공능지표.결과 본조자료중발생심쇠공23.6%(56/237),기중족궤양조27.2%(44/162),균위좌실사혈분수정상심공능불전.입원시총체환병솔위8.9%(21/237),기중족부궤양조10.5%(17/162),여족궤양고위조상비차이유통계학의의(P＜0.01);재주원치료기간,심쇠신증가14.8%(35/237),기중족궤양조위16.7%(27/162),균발생재치료후2~7 d,고봉재치료후제4천;치료후발생적심쇠재족궤양Wagner분급각조간차이유통계학의의(P＜0.05);심쇠경치료후심공능균개선병능내수족궤양적치료.결론 당뇨병족궤양재치료전화치료중유교고적좌실사혈분수정상심공능불전환병솔.
Objective To estimate heart function among patients with diabetic foot ulcer,and to investigate the characteristics of heart failure(HF) before and after treatment of ulcer. Methods Items associated with diabetes and some physiological and biochemical indicators were observed in patients with diabetic foot ulcer(162 cases) and with high risk factors of ulcer(75 cases). Heart function was evaluated at patients′ admission, during ulcer related treatment, and prior to discharge. Left ventricular ejection fraction and other cardiac assessment were measured with ultrasonic scan.Results During hospitalization, 23.6%(56/237) patients underwent HF with normal left ventricular ejection fraction, and it was 27.2%(44/162) in patients with foot ulcers. The prevalence of HF was 8.9%(21/237) in all patients studied on admission, and that was 10.5%(17/162) in patients with foot ulcer, more than that without foot ulcer(P＜0.01). More patients with HF were found, being 14.8%(35/237) during 2-7 days after ulcer related treatment initiated, and peak was on the 4th day. There was statistical difference among different Wagner grades(P＜0.05) about the morbidity rate of HF. All patients with HF were improved and tolerant to ulcer related treatment. Conclusion The prevalence of HF with normal left ventricular ejection fraction was relatively high in patients with diabetic foot ulcer, especially after ulcer treatment.
