中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2012年
8期
512-515
,共4页
王进有%沈益君%刘小航%张海梁%叶定伟%姚旭东%张世林%戴波%朱耀%周良平
王進有%瀋益君%劉小航%張海樑%葉定偉%姚旭東%張世林%戴波%硃耀%週良平
왕진유%침익군%류소항%장해량%협정위%요욱동%장세림%대파%주요%주량평
前列腺肿瘤%磁共振成像%超声检查
前列腺腫瘤%磁共振成像%超聲檢查
전렬선종류%자공진성상%초성검사
Prostate neoplasms%Magnetic resonance imaging%Ultrasonography
目的 检测弥散加权磁共振(MRDWI)诊断前列腺癌的敏感度和特异度.方法 回顾性分析2009年1月至2010年12月在复旦大学附属肿瘤医院泌尿外科行MRDWI联合经直肠超声( TRUS)定位下前列腺穿刺的141例患者资料,按前列腺特异抗原(PSA) <10 μg/L、10 μg/L≤PSA<20 μg/L、20 μg/L≤PSA <50.μg/L和PSA≥50 μg/L将可疑患者分为4组(A~D),按照前列腺6分区法将所得图像数据分区测量,统计各区的影像学诊断及对应穿刺标本的病理,并分别计算MRDWI和TRUS的敏感度和特异度.结果 A、B、C、D4组的穿刺诊断率分别为23.7%、35.5%、66.7%和96.3%.MRDWI敏感度显著优于TRUS,以患者为研究单位时,MRDWI在PSA< 10μg/L、10 μg/L≤PSA <20 μg/L、20 μg/L≤PSA< 50μg/L和PSA≥50 μg/L的患者中诊断敏感度分别为85.7%、72.7%、97.8%和100.0%,TRUS在各组对应的诊断敏感度为35.7%、36.4%、43.8%和65.4%.以穿刺标本为研究单位时,MRDWI在各组的诊断敏感度分别为85.5%、71.9%、91.5%和94.4%,TRUS在各组对应的敏感度为23.4%、34.5%、68.9%和89.3%.结论 MR弥散加权成像诊断前列腺癌的初步结果显示其敏感度显著优于TRUS,且临床操作便捷、高效.对于前列腺癌可疑患者,建议行MRDWI及TRUS联合定位的可疑病灶加系统穿刺法.
目的 檢測瀰散加權磁共振(MRDWI)診斷前列腺癌的敏感度和特異度.方法 迴顧性分析2009年1月至2010年12月在複旦大學附屬腫瘤醫院泌尿外科行MRDWI聯閤經直腸超聲( TRUS)定位下前列腺穿刺的141例患者資料,按前列腺特異抗原(PSA) <10 μg/L、10 μg/L≤PSA<20 μg/L、20 μg/L≤PSA <50.μg/L和PSA≥50 μg/L將可疑患者分為4組(A~D),按照前列腺6分區法將所得圖像數據分區測量,統計各區的影像學診斷及對應穿刺標本的病理,併分彆計算MRDWI和TRUS的敏感度和特異度.結果 A、B、C、D4組的穿刺診斷率分彆為23.7%、35.5%、66.7%和96.3%.MRDWI敏感度顯著優于TRUS,以患者為研究單位時,MRDWI在PSA< 10μg/L、10 μg/L≤PSA <20 μg/L、20 μg/L≤PSA< 50μg/L和PSA≥50 μg/L的患者中診斷敏感度分彆為85.7%、72.7%、97.8%和100.0%,TRUS在各組對應的診斷敏感度為35.7%、36.4%、43.8%和65.4%.以穿刺標本為研究單位時,MRDWI在各組的診斷敏感度分彆為85.5%、71.9%、91.5%和94.4%,TRUS在各組對應的敏感度為23.4%、34.5%、68.9%和89.3%.結論 MR瀰散加權成像診斷前列腺癌的初步結果顯示其敏感度顯著優于TRUS,且臨床操作便捷、高效.對于前列腺癌可疑患者,建議行MRDWI及TRUS聯閤定位的可疑病竈加繫統穿刺法.
목적 검측미산가권자공진(MRDWI)진단전렬선암적민감도화특이도.방법 회고성분석2009년1월지2010년12월재복단대학부속종류의원비뇨외과행MRDWI연합경직장초성( TRUS)정위하전렬선천자적141례환자자료,안전렬선특이항원(PSA) <10 μg/L、10 μg/L≤PSA<20 μg/L、20 μg/L≤PSA <50.μg/L화PSA≥50 μg/L장가의환자분위4조(A~D),안조전렬선6분구법장소득도상수거분구측량,통계각구적영상학진단급대응천자표본적병리,병분별계산MRDWI화TRUS적민감도화특이도.결과 A、B、C、D4조적천자진단솔분별위23.7%、35.5%、66.7%화96.3%.MRDWI민감도현저우우TRUS,이환자위연구단위시,MRDWI재PSA< 10μg/L、10 μg/L≤PSA <20 μg/L、20 μg/L≤PSA< 50μg/L화PSA≥50 μg/L적환자중진단민감도분별위85.7%、72.7%、97.8%화100.0%,TRUS재각조대응적진단민감도위35.7%、36.4%、43.8%화65.4%.이천자표본위연구단위시,MRDWI재각조적진단민감도분별위85.5%、71.9%、91.5%화94.4%,TRUS재각조대응적민감도위23.4%、34.5%、68.9%화89.3%.결론 MR미산가권성상진단전렬선암적초보결과현시기민감도현저우우TRUS,차림상조작편첩、고효.대우전렬선암가의환자,건의행MRDWI급TRUS연합정위적가의병조가계통천자법.
Objective To retrospectively analyze the clinical value of difftision-weighted magnetic resonance imaging (MRDWI) in the detection of prostate cancer in suspected patients.Methods Between January 2009 and December 2010,141 patients with suspected prostate cancer underwent MRDWI and transrectal ultrasound (TRUS) guided prostate biopsy.They were divided into 4 groups by prostate surface antigen (PSA) <10 μg/L,10 μg/L≤PSA <20 μg/L,20 μg/L≤PSA <50 μg/L and PSA≥50 μg/LThen the diagnostic accuracy of MRDWI was tested.Results The diagnostic rate of patients with PSA <10 μg/L,10 μμg/L ≤ PSA < 20 μg/L,20 μg/L ≤ PSA < 50 μg/L and PSA ≥ 50 μg/L were 23.7%,35.5%,66.7% and 96.3% respectively.The sensitivity of MRDWI was significantly better than TRUS.In patients with PSA < 10 μg/L,10 μg/L≤PSA <20 μμg/L,20 μg/L-≤PSA <50 μg/L and PSA≥50 μg/L,the patient-based sensitivities were 85.7%,72.7%,97.8%,100.0% respectively; when based by segment of specimen,the sensitivities were 85.5%,71.9%,91.5% and 94.4% respectively.Conclusion The sensitivity of MDWI is significantly better than TRUS in the diagnosis of prostate cancer.The combined use of MDWI and TRUS has the benefit of guiding the biopsy of cancer foci in patients with suspected prostate cancer.