CAJ | 학술논문

利用核磁共振碳谱、磷谱、氢谱对甘氨酸法合成草甘膦的各阶段反应进行定量跟踪分析, 发现由甲醛引起的副反应是影响草甘膦收率的重要因素之一,证实了羟甲基亚瞵酸、增甘膦、N-甲基草甘膦和亚磷酸是甘氨酸法合成草甘膦的主要副产物,减少或抑制其生成是草甘膦合成工艺优化的关键.探讨了抑制副反应发生的条件,对甘氨酸法合成草甘膦工艺优化有重要的理论指导意义.
이용핵자공진탄보、린보、경보대감안산법합성초감련적각계단반응진행정량근종분석, 발현유갑철인기적부반응시영향초감련수솔적중요인소지일,증실료간갑기아린산、증감련、N-갑기초감련화아린산시감안산법합성초감련적주요부산물,감소혹억제기생성시초감련합성공예우화적관건.탐토료억제부반응발생적조건,대감안산법합성초감련공예우화유중요적이론지도의의.
It was found that the side-reactions caused by formaldehyde is an important influence factor in the synthesis of glyphosate started from glycine by analysis with ~(13)C NMR, ~(31)P NMR, and ~1H NMR. Hydroxymethyl phosphonic acid, Polaris, N-(methylation)glyphosate and phosphite were the main by-products and reducing or restraining the generation of them is the crux of optimizing glyphosate technique. Optimizing the technique of synthesizing glyphosate starting from glycine has great significance in theory.