国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
INTERNATIONAL JOURNAL OF IMMUNOLOGY
2008年
4期
260-262
,共3页
CD4+ CD25+调节性T细胞%免疫调节%肾脏疾病
CD4+ CD25+調節性T細胞%免疫調節%腎髒疾病
CD4+ CD25+조절성T세포%면역조절%신장질병
CD4+ CD25+ regulatory T cells%Immunological regulation%Kidney diseases
CD4+ CD25+ 调节性T细胞(Tr)是一个具有独立功能的T细胞亚群,是机体维持自身免疫耐受的重要组成部分,在免疫病理、移植物耐受、阻止自身免疫反应和维持机体免疫平衡方面都有一定作用,其T细胞亚群在多种免疫性疾病中发挥重要的调节作用,但国内外有关该群细胞在肾脏疾病中作用的报道较少.
CD4+ CD25+ 調節性T細胞(Tr)是一箇具有獨立功能的T細胞亞群,是機體維持自身免疫耐受的重要組成部分,在免疫病理、移植物耐受、阻止自身免疫反應和維持機體免疫平衡方麵都有一定作用,其T細胞亞群在多種免疫性疾病中髮揮重要的調節作用,但國內外有關該群細胞在腎髒疾病中作用的報道較少.
CD4+ CD25+ 조절성T세포(Tr)시일개구유독립공능적T세포아군,시궤체유지자신면역내수적중요조성부분,재면역병리、이식물내수、조지자신면역반응화유지궤체면역평형방면도유일정작용,기T세포아군재다충면역성질병중발휘중요적조절작용,단국내외유관해군세포재신장질병중작용적보도교소.
CD4+ CD25+ regulatory T ceHs(Tr),a subset of T cells with independent function ale present in the normal immune system as an essential cellular component for maintaining autoimmune tolerance and immune homeostasis.They play an important role in immunopathogenesis, transplant tolerance,preventing autoimmune response and keeping immunologic balance.Researchs suggested that CD4+ CD25+ regulatory T cells ale of critical importance in many immunological diseases,but there ale few reports concerning the role of these cells in kidney diseases.
