中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
6期
747-748
,共2页
肿瘤坏死因子%白细胞介素6%早产%宫内感染
腫瘤壞死因子%白細胞介素6%早產%宮內感染
종류배사인자%백세포개소6%조산%궁내감염
Tumor necrosis factor-α%Interleukin- 6%Preterm labor%Intrauterine infection
目的 探讨肿瘤坏死因子(TNF-α)、白细胞介素-6(IL-6)与早产发病的关系.方法 采用酶联免疫吸附法(ELISA)检测58例早产患者(根据胎盘病检有无绒毛膜羊膜炎分为早产感染组32例和早产非感染组26例)及同期足月正常产28例母血清TNF-α、IL-6的水平.结果 早产感染组孕妇血清中TNF-α、IL-6水平明显高手早产非感染组和正常足月产组,差异有显著性(P<0.05).结论 TNF-α和IL-6水平与感染性早产密切相关;TNF-α和IL-6含量的联合检测为感染性早产因素提供了客观、可靠的依据,有助于提高早产的预测价值.
目的 探討腫瘤壞死因子(TNF-α)、白細胞介素-6(IL-6)與早產髮病的關繫.方法 採用酶聯免疫吸附法(ELISA)檢測58例早產患者(根據胎盤病檢有無絨毛膜羊膜炎分為早產感染組32例和早產非感染組26例)及同期足月正常產28例母血清TNF-α、IL-6的水平.結果 早產感染組孕婦血清中TNF-α、IL-6水平明顯高手早產非感染組和正常足月產組,差異有顯著性(P<0.05).結論 TNF-α和IL-6水平與感染性早產密切相關;TNF-α和IL-6含量的聯閤檢測為感染性早產因素提供瞭客觀、可靠的依據,有助于提高早產的預測價值.
목적 탐토종류배사인자(TNF-α)、백세포개소-6(IL-6)여조산발병적관계.방법 채용매련면역흡부법(ELISA)검측58례조산환자(근거태반병검유무융모막양막염분위조산감염조32례화조산비감염조26례)급동기족월정상산28례모혈청TNF-α、IL-6적수평.결과 조산감염조잉부혈청중TNF-α、IL-6수평명현고수조산비감염조화정상족월산조,차이유현저성(P<0.05).결론 TNF-α화IL-6수평여감염성조산밀절상관;TNF-α화IL-6함량적연합검측위감염성조산인소제공료객관、가고적의거,유조우제고조산적예측개치.
Objective To investigate the role of tumor necrosis factor-α(TNF-α) and: Interleukin-6 (IL-6) in preterm labor. Methods We collected 58 cases maternal serum and partial placental tissues of preterm labor (32 cases of infectious group with chorioamnionitis, 26 cases of noninfectious group without chorioamnionitis), and 28 cases maternal serum of term labor in corresponding period were collected. In 86 cases serum levels of TNF-α and IL-6 were measured by enzyme -linked immunosorbent assay (ELISA). Results The levels of maternal serum TNF-α and IL-6 in preterm labor with chorioamnionitis were significantly higher than those of preterm labor without chorioamnionitis and term labor( P < 0.05 ). Conclusion The increase of TNF-α and IL-6 level is closely related to preterm labor with chorioamnionitis, and the detecting of TNF-α and IL-6 level is valuable in predicting premature delivery.
