中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
7期
861-862
,共2页
骨肽注射剂%过敏性休克%药品不良反应%合理用药
骨肽註射劑%過敏性休剋%藥品不良反應%閤理用藥
골태주사제%과민성휴극%약품불량반응%합리용약
Gutai injection%Anaphylactic shook%Adverse drug reaction%Rational use of drug
目的 探讨骨肽注射剂致过敏性休克的临床特点及发生规律,为临床合理用药提供参考.方法 对2005-2010年中国期刊全文数据库进行检索,对其中涉及骨肽注射剂致过敏反应的25例病例报告进行统计与分析.结果 共检索到骨肽注射剂致过敏性休克的文献30篇,涉及患者25例.骨肽注射剂致过敏性休克患者(25例,261例次)的临床表现以心血管系统损害、中枢神经系统损害、呼吸系统损害较为多见.呼吸系统损害最多,占30.3％(79/261).其次为心血管系统损害,占19.9％ (52/261);中枢神经系统占18.0％(47/261).结论 骨肽注射剂导致过敏性休克发生时间短,多在用药过程中半小时内发生,病情危重,以呼吸系统、心血管系统和中枢神经系统损害多见.骨肽注射剂自身因素是导致过敏性休克的主要原因,应引起临床高度重视.
目的 探討骨肽註射劑緻過敏性休剋的臨床特點及髮生規律,為臨床閤理用藥提供參攷.方法 對2005-2010年中國期刊全文數據庫進行檢索,對其中涉及骨肽註射劑緻過敏反應的25例病例報告進行統計與分析.結果 共檢索到骨肽註射劑緻過敏性休剋的文獻30篇,涉及患者25例.骨肽註射劑緻過敏性休剋患者(25例,261例次)的臨床錶現以心血管繫統損害、中樞神經繫統損害、呼吸繫統損害較為多見.呼吸繫統損害最多,佔30.3％(79/261).其次為心血管繫統損害,佔19.9％ (52/261);中樞神經繫統佔18.0％(47/261).結論 骨肽註射劑導緻過敏性休剋髮生時間短,多在用藥過程中半小時內髮生,病情危重,以呼吸繫統、心血管繫統和中樞神經繫統損害多見.骨肽註射劑自身因素是導緻過敏性休剋的主要原因,應引起臨床高度重視.
목적 탐토골태주사제치과민성휴극적림상특점급발생규률,위림상합리용약제공삼고.방법 대2005-2010년중국기간전문수거고진행검색,대기중섭급골태주사제치과민반응적25례병례보고진행통계여분석.결과 공검색도골태주사제치과민성휴극적문헌30편,섭급환자25례.골태주사제치과민성휴극환자(25례,261례차)적림상표현이심혈관계통손해、중추신경계통손해、호흡계통손해교위다견.호흡계통손해최다,점30.3％(79/261).기차위심혈관계통손해,점19.9％ (52/261);중추신경계통점18.0％(47/261).결론 골태주사제도치과민성휴극발생시간단,다재용약과정중반소시내발생,병정위중,이호흡계통、심혈관계통화중추신경계통손해다견.골태주사제자신인소시도치과민성휴극적주요원인,응인기림상고도중시.
Objective To study clinic features and regularity of anaphylactic shock induced by Gutai injection and to provide reference for rational use of drug.Methods Twenty-five cases of allergic reaction induced by Gutai injection were collected and analyzed from China National Knowledge Infrastructure(CNKI) articles in 2005-2010.Results All 30 articles of anaphylactic Gutai injection,including 25 patients,were analyzed.The damage of cardiovascular system central nervous system and respiratory system were common in anaphylactic shock with Gutai injection.Respiratory system harms were up to 30.3％(79/261).Secondly the cardiovascular system harms were up to 19.9 ％(52/261);central nervous system was up to 18.0％(47/261).Conclusion The duration of anaphylactic shook with Gutai injection is short.It usually happens within 30 minutes after injection and critical illness.
